I am now an Assistant Professor at the Medical School of Nanjing University. From March 2019 to April 2023, I was an Associate Researcher at the School of Electrical Science and Technology of Nanjing University and a member of CITE Lab.

I am currently working with Prof. Ning Gu and Prof. Xun Cao. My research interests include Computational Optics and Microscopy, especially focusing on designing novel and miniaturized microscopes (on-chip microscope, light-field microscope, and micro-endoscope) and developing iterative/intelligent algorithms based on physical imaging processes (3D fluorescent imaging and 3D echocardiogram). For students who are interested in our research area, welcome to join us.

• Ph. D. 2012.08 – 2019.01, Broadband Network and Digital Media Lab (BBNC), Department of Automation, Tsinghua University, Beijing, China. Supervisor: Prof. Qionghai Dai.
• Visiting Student. 2016.12 – 2017.06, Smart Imaging Lab, Biomedical Engineering Department, University of Connecticut (Uconn), Storrs, Connecticut, USA. Supervisor: Prof. Guoan Zheng.
• Bachelor of Science. 2008.09 – 2012.07, Department of Communication Engineering, East China Normal University, Shanghai, China.
• Minor Degree. 2009.09 – 2012.02, School of Mathematical Sciences, Shanghai Jiaotong University, Shanghai, China.

• 2025: Hao Wu (Ph. D.) Zhiyuan Deng (Ph. D.)
• 2024: Wei Li (M.S.) Chenyu Xu (M.S.) Yixiao Ma (M.S.) Zhouyu Jin (Ph. D.) Xinyue Ge (Ph. D.)
• 2023: Bohan Qu (M.S.) Meiyue Wang (Ph. D.)
• 2021: Yunzhong Zhang (Ph. D.)
• 2020: Weizhi Song (Ph. D.)

• 2022.09-2025.06 Junjia Wang (M.S.) Now at Huawei (Shanghai)
• 2021.09-2024.06 Yifei Liu (M.S.) Now at Suyin Wealth Management (Nanjing)
• 2020.09-2024.06 Zhouyu Jin (M.S. and then Research Assistant) Now Ph.D. (NJU)

1. Journal Paper

2025

• B. Qu*, Z. Jin*, Y. Zhou#, B. Xiong#, X. Cao. Deep learning-based noise correction method for light-field fluorescence microscopy. Photonics Research, 2025, 13(9):2547.
• C. Xu*, Z. Jin*, C. Shen, H. Zhu, Z. Ma, B. Xiong#, Y. Zhou#, X. Cao, N. Gu. 3D Gaussian Adaptive Reconstruction for Fourier Light-Field Microscopy. Advanced Imaging, 2025, 2(5), 055001. (On the Cover)
• J. Wang*, B. Xiong*, Y. Zhou#, X. Cao, Z. Ma. VM-GAN: A Value Mapping Framework for Virtual Staining of Optical Microscopy Images. Optics Express, 2025, 33(12), 25641-25655.
• C. Su*, Y. Chen*, Z. Lin, Y. Zhou, B. Xiong, Z. Yu, T. Huang. Inter-event Interval Microscopy for Event Cameras. Photonics Research, 2025, 13(10), 2843-2853.

2024

• Y. Zhou*, W. Song*, L. Wu, L. Fan, J. Wang, S. Jiang, Z. Ma, B. Xiong#, X. Cao#. Large-scale lensless microscopy with fast acquisition and region-wise focusing. Laser & Photonics Reviews, 2024, 18(10), 2400498.
• C. Shen*, H. Zhu*, Y. Zhou*, Y. Liu, S. Yi, L. Dong, W. Zhao, D. Brady, X. Cao#, Z. Ma#, Y. Lin#. Continuous 3D Myocardial Motion Tracking via Echocardiography. IEEE Transactions on Medical Imaging, 2024, 43(12).
• C. Shen*, H. Zhu*, Y. Zhou*, Y. Liu*, S. Yi, L. Dong, W. Zhao#, D. Brady, X. Cao#, Z. Ma#, Y. Lin#. CardiacField: Computational Echography for Automated Heart Function Estimation Using 2DE Probes. Europoean Heart Journal - Digital Health, 2024, ztae072.
• C. Su, Z. Lin, Y. Zhou, S. Wang, Y. Gao, C. Yan, B. Xiong#. PC-bzip2: a phase-space continuity-enhanced lossless compression algorithm for light-field microscopy data. Advanced Photonics Nexus, 2024, 3(3), 036005.
• H. Zhu, S. Xie, Z. Liu, F. Liu, Q. Zhang, Y. Zhou, Y. Lin, X. Cao. Disorder-Invariant Implicit Neural Representation. IEEE Transactions on Pattern Analysis and Machine Intelligence, 2024, 46(8).
• B. Xiong, C. Su, Z. Lin, Y. Zhou, Z. Yu, INeAT: an artifact-suppressed and resolution-enhanced computed tomography through iterative neural adaptive tomography. Optics Express, 2024, 32(18), 32336.
• 蒋青, 徐标, 龚旺, 王鹏, 刘吉梓, 周游, 孙璇, 鲍雪, 徐运, 张冰, 吕晗, 段红霞, 王振常#, 阎锡蕴#, 顾宁#. 血管-神经-淋巴网络稳态与失衡对健康评估的价值. 中华医学杂志, 2024,104(15)：1323-1330.

2023

• Y. Zhou*, Z. Jin*, Q. Zhao, B. Xiong#, X. Cao#. Aberration modeling in deep learning for volumetric reconstruction of light-field microscopy. Laser & Photonics Reviews, 2023, 17(10), 2300154.
• L. Chen, L. Cai, E. Huang, Y. Zhou#, T. Yue, X. Cao. A notch-mask and dual-prism system for snapshot spectral imaging. Optics and Lasers in Engineering, 2023, 165, 107544.
• C. Su, Y. Gao, Y. Zhou, Y. Sun, C. Yan, H. Yin, B. Xiong#. AutoDeconJ: a GPU accelerated ImageJ plugin for 3D light field deconvolution with optimal iteration numbers predicting. Bioinformatics, 2023, 39(1), btac760.
• P. Song, T. Wang, S. Jiang, C. Guo, R. Wang, L. Yang, Y. Zhou, G. Zheng#. Freeform illuminator for computational microscopy. Intelligent Computing, 2023, 2, 0015.
• 刘振, 朱昊, 周游, 马展, 曹汛#. 物理模型引导的智能相位成像 (Intelligent phase imaging guided by physics models).物联网学报 (Chinese Journal on Internet of Things), 2023, 7(2), 35-42.
• 朱昱敏, 刘吉梓, 周游, 王方旭, 潘鸣飞, 张方舟, 曹晨, 沈艳, 顾宁#. 细胞生物信息学应用于疾病诊断的前景. 广西医科大学学报, 2023, v.40 (04), 533-542.

2022

• Y. Zhou*, B. Xiong*, W. Song, X. Zhang, G. Zheng, Q. Dai#, X. Cao#. Light-field micro-endoscopy using a fiber bundle: a snapshot 3D epi-fluorescence endoscope. Photonics Research, 2022, 10(9), 2247-2260. (Editor's Pick)
• X. Hua*, Y. Wang*, S. Wang*#, X. Zou, Y. Zhou, L. Lin, F. Yan, X. Cao#, S. Xiao#, D. Tsai#, J. Han, Z. Wang#, S. Zhu#. Ultra-compact snapshot spectral light-field imaging. Nature Communications, 2022, 13, 2732.
• H. Zhu*, Z. Liu*, Y. Zhou#, Z. Ma, X. Cao#. DNF: Diffractive Neural Field for Lensless Microscopic Imaging. Optics Express, 2022, 30(11), 18168-18178.
• Y. Guo, R. Guo, Q. Pan, Y. Zhou, Z. Zhang#, G. Zheng, J. Zhong. Robust multi-angle structured illumination lensless microscopy via illumination angle calibration. Optics Letters, 2022, 47(7), 1847-1850.

2021

• C. Lu*, Y. Zhou*, Y. Guo*, S. Jiang, Z. Zhang#, G. Zheng, J. Zhong. Mask-modulated lensless imaging via translated structured illumination. Optics Express, 2021, 29(8), 12491-12501.
• B. Xiong*, X. Li*, Y. Zhou, L. Wang, J. Wu, Q. Dai#. Snapshot Partially Coherent Diffraction Tomography. Physical Review Applied, 2021, 15(4), 044048.

• Y. Zhou*, B. Xiong*, X. Li, Q. Dai, X. Cao#. Lensless imaging of plant samples using the cross-polarized light. Optics Express, 2020, 28(21), 31611-31623.
• Y. Zhou*, X. Hua*, Z. Zhang, X. Hu, K. Dixit, J. Zhong, G. Zheng, X. Cao#. Wirtinger gradient descent optimization for reducing Gaussian noise in lensless microscopy. Optics and Lasers in Engineering, 2020, 134, 106131.
• X. Hua, Y. Cai, Y. Zhou, F. Yan, X. Cao#. Leukocyte super-resolution via geometry prior and structural consistency. Journal of Biomedical Optics, 2020, 25(10), 106501-106501.

• Z. Lu, J. Wu, H. Qiao, Y. Zhou, T. Yan, Z. Zhou, X. Zhang, J. Fan, Q. Dai#. Phase-space deconvolution for light field microscopy. Optics Express, 2019, 27(13), 18131-18145.
• Y. Zhou, J. Wu, J. Suo, X. Han, G. Zheng, Q. Dai#. Single-shot lensless imaging via simultaneous multi-angle LED illumination. Optics Express, 2018, 26(17), 21418-21432.
• Z. Zhang*, Y. Zhou*, S. Jiang, K. Guo, K. Hoshino, J. Zhong, J. Suo, Q. Dai, G. Zheng#. Invited Article: Mask-modulated lensless imaging with multi-angle illuminations. APL Photonics, 2018, 3(6), 060803.
• Y. Zhou, J. Wu, Z. Bian, J. Suo, G. Zheng, Q. Dai#. Fourier ptychographic microscopy using wavelength multiplexing. Journal of Biomedical Optics, 2017, 22(6), 066006.
• X. Wang, Q. Zhang, Y. Zhou, J. Qian, H. Zou#. Linear canonical transform related operators and their applications to signal analysis—Part I: Fundamentals. Chinese Journal of Electronics, 2015, 24(1), 102-109.
• X. Wang, Q. Zhang, Y. Zhou, J. Qian, H. Zou#. Linear Canonical Transform Related Operators and Their Applications to Signal Analysis—Part II: Applications. Chinese Journal of Electronics, 2015, 24(2), 312-316.

2. Conference Paper

Artificial Intelligence

• Y. Zhang*, Y. Zhou*, C. Su, Z. Cheng, Z. Yu, B. Xiong#, T. Huang, X. Cao. Spike Imaging Velocimetry: Dense Motion Estimation of Fluids Using Spike Streams. AAAI Conference on Artificial Intelligence (AAAI), Singapore, 2026.
• B. Jiang*, B. Xiong*, B. Qu, M. S. Asif, Y. Zhou#, Z. Ma#. EDformer: Transformer-Based Event Denoising Across Varied Noise Level. European Conference on Computer Vision (ECCV), Milan, Italy, 2024.
• H. Ge, Q. Feng, H. Jia, X. Li, X. Yin, Y. Zhou, J. Yang, K. Li#. LPSNet: End-to-End Human Pose and Shape Estimation with Lensless Imaging. IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Seattle, USA, 2024.
• C. Su, Z. Ye, Y. Xiao,  Y. Zhou, Z. Cheng, B. Xiong, T. Huang. Intensity-robust autofocus for spike camera. IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Seattle, USA, 2024.
• B. Xiong, C. Su, Z. Lin, Y. Chen,  Y. Zhou, Z. Cheng, T. Huang. Real-time parameter evaluation of high-speed microfluidic droplets using continuous spike streams. ACM International Conference on Multimedia (ACM MM), Melbourne VIC, Australia, 2024.
• S. Xie*, H. Zhu*, Z. Liu, Q. Zhang, Y. Zhou, X. Cao#, Z. Ma#. DINER: Disorder-Invariant Implicit Neural Representation. IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Vancouver, Canada, 2023. (Highlight, 2.5% of submissions)

Optics and Photonics

• C. Xu, Z. Jin, B. Xiong, Y. Zhou#, X. Cao. 3D Image Restoration using Implicit Neural Representations for Brightfield and Widefield Fluorescence Microscopy. Computational Optical Sensing and Imaging (COSI), France, Toulouse, 2024.
• Y. Liu, W. Song, Y. Zhou#, B. Xiong, X. Cao. Hybrid Scanning Lensless Imaging by Diffractive Neural Field. Computational Optical Sensing and Imaging (COSI), France, Toulouse, 2024.
• B. Xiong, R. Wang, Y. Zhou, X. Sun, Y. Yang, C. Su. High-speed phase transition imaging using spike streams. 3D Image Acquisition and Display: Technology, Perception and Applications, France, Toulouse, 2024.
• Y. Zhou, B. Xiong#, W. Song, X. Cao. Dual-modal light-field micro-endoscopy. Frontiers in Optics + Laser Science (FiO+LS), Optica Publishing Group, New York, USA, 2022.
• W. Song, Y. Zhou#, B. Xiong, X. Cao. Lensless Imaging By Binary Mask Rotation. Frontiers in Optics + Laser Science (FiO+LS), Optica Publishing Group, New York, USA, 2022.
• C. Su, T. Liu, C. Chen, H. Wang, J. Hu, Y. Zhou#, B. Xiong#, X. Cao. Analysis of pre-processing methods for lossless compression of multi–component medical images based on latent variable models. Frontiers in Optics + Laser Science (FiO+LS), Optica Publishing Group, New York, USA, 2022.
• W. Song, Y. Zhou#, B. Xiong, X. Cao. Multi-wavelength Lensless Microscopy Via A Linear Variable Bandpass Filter. Biophotonics Congress: Biomedical Optics, Optica Publishing Group, Florida, USA, 2022.
• Y. Zhou, X. Hua, W. Song, X. Cao#. A novel denoising reconstruction algorithm for multi-height lensless microscopy. Biophotonics Congress: Biomedical Optics, Optical Society of America, Washington D.C., USA, 2020.
• Y. Zhou, G. Zhang, J. Wu, M. Choi, Q. Dai#. Wavefront shaping for achieving high NA GRIN-lens-based endoscopic imaging. Biophotonics Congress: Optics in the Life Sciences, Optical Society of America, Arizona, USA, 2019.
• Y. Zhou, J. Wu, Z. Bian, G. Zheng, Q. Dai#. Wavelength multiplexed Fourier ptychographic microscopy. Computational Optical Sensing and Imaging (COSI), Optical Society of America, Heidelberg, Germany, 2016.

3. Granted Patent

• Q. Dai, Y. Zhou, J. Wu, and G. Zhang. Microscopic Imaging system and method. USA, US11262568B2.
• Q. Dai, Y. Zhou, J. Wu, and J. Fan. Wavelength multiplexed Fourier ptychographic microscopy system and method. USA, US10185137B2.
• Q. Dai, Y. Zhou, J. Wu, and G. Zhang. Rapid three-dimensional imaging system and method based on multi-angle 4Pi microscope, and storage medium. USA, US11719921B2.

Reviewer (since 2019):

Jiangsu Young Talent Support Program, Jiangsu Province, China, 2025
Doctor of Innovation and Entrepreneurship, Jiangsu Province, China, 2020
Short-term Overseas Exchange Scholarship of Tsinghua University, 2016
Best Oral Presentation in the PhD Forum of Tsinghua University, 2015
Excellent Laboratory Construction Award of Tsinghua University, first prize, 2015
Technological Invention Award of Shanghai University Student, third prize, 2012
Technological Invention Award of East China Normal University, first prize, 2011
Excellent Student of East China Normal University, 2010
Outstanding Student Scholarship of East China Normal University (3 times), 2008-2012

3D Gaussian adaptive reconstruction for Fourier light-field microscopy

CardiacField: Computational Echocardiography for Automated Heart Function Estimation Using 2DE Probes

Continuous 3D Myocardial Motion Tracking via Echocardiography

DINER: Disorder-Invariant Implicit Neural Representation

DNF: Diffractive Neural Field for Lensless Microscopic Imaging

Wirtinger gradient descent optimization for reducing Gaussian noise in lensless microscopy