| CARVIEW |
Lequan YuAssistant Professor
Rm 226, Run Run Shaw Building |
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Biography
I am an assistant professor at The University of Hong Kong, where I direct the Medical AI Lab. My research lies at the intersection of artificial intelligence and healthcare. We are dedicated to designing advanced computational and machine learning algorithms for biomedical data analysis, primarily focusing on medical images, to improve medical decision-making. Specifically, we focus on: 1) developing multimodal learning algorithms (e.g., multimodal foundation model) to integrate multi-scale biomedical data for disease prevention, diagnosis, prognosis, and treatment design; 2) building real-world learning systems to learn generalizable, trustworthy, and fair representations from imperfect biomedical data; and 3) leveraging statistical learning tools (e.g., causal inference) to improve their interpretability, robustness, and safety for healthcare problems.
Before joining HKU, I was a postdoctoral research fellow at Stanford University. I obtained my Ph.D. degree in CSE, The Chinese University of Hong Kong in 2019 and the B.Eng degree in CS, Zhejiang University in 2015.
Recent focus: 1) LLM/VLM/Agentic AI for Healthcare, 2) Multimodal Learning, 3) Computational Pathology, and 4) Biomedical Informatics
We are looking for self-motivated Postdoc/PhD/RA/Interns, who are interested in medical AI.
Please drop me an email with your CV and transcripts.
You are also welcome to apply for the HKU-BICI Joint PhD Programme
and HKU-ASTRI Joint PhD Programme.
If you are an HKU student interested in doing research with me, please send me an email.
News
- [12/2025] Two papers were accepted by TMI.
- [11/2025] Invited to serve as Guest Associated Editor, IEEE Transactions on Medical Imaging (TMI).
- [11/2025] Two papers were accepted by AAAI 2026.
- [11/2025] Our pathology FM adaptation work was accepted by Nature Communications.
- [09/2025] Three papers were accepted by NeurIPS 2025.
- [08/2025] Invited to serve as Area Chair of ICLR 2026 and CVPR 2026.
- [08/2025] Our Hist2cell work is accepted by Cell Genomics.
- [08/2025] Recent publications in 2025 Summer: 2 TPAMI, 1 TMI, 2 ICML, 1 ACL, and 3 MICCAI.
- [06/2025] Invited to serve as Area Chair of AAAI 2026.
- [04/2025] Invited to be an Associate Editor of npj Digital Medicine.
- [04/2025] Invited to serve as Area Chair of NeurIPS 2025.
- [04/2025] The 3rd Workshop on Computer Vision for Automated Medical Diagnosis will appear in ICCV 2025.
- [02/2025] The 2nd tutorial on GraphMedIA: Graph Learning in Medical Image Analysis will appear in MICCAI 2025.
- [02/2025] One paper was accepted by TMI.
- [12/2024] One paper was accepted by npj Digital Medicine.
- [12/2024] Two papers were accepted by AAAI 2025.
- [10/2024] One paper was accepted by TMI.
- [09/2024] One paper was accepted by NeurIPS 2024.
- [09/2024] One paper was accepted by TPAMI.
- [08/2023] Recent publications in 2024 Summer: 1 MedIA, 1 NN, 1 JBHI, 2 ECCV.
- [06/2024] Three papers were accepted by MICCAI 2024.
- [02/2024] One paper was accepted by CVPR 2024.
- [01/2024] Invited to serve as Area Chair in MICCAI 2024.
- [12/2023] Two papers were accepted by AAAI 2024.
- [09/2023] Two papers were accepted by NeurIPS 2023.
- [07/2023] Recent publications in 2023 Summer: 1 TPAMI, 2 TMI, 1 TIP, 1 JBHI, 1 ICCV, 5 MICCAI.
- [04/2023] One co-authored paper was accepted by Radiology: Artificial Intelligence.
- [03/2023] Three papers were accepted by CVPR 2023.
- [01/2023] Invited to serve as Area Chair in MICCAI 2023.
- [11/2022] One co-authored paper was accepted by Nature Communications.
- [10/2022] Ranked Top 2% of Scientists on Stanford List.
- [09/2022] Our MICCAI CMMCA workshop paper got the Best Paper Award.
- [09/2022] Our MICCAI DART workshop paper got the Best Paper Honorable Mention Award.
- [04/2022] Named on the World's First List of Top 150 Chinese Young Scholars in Artificial Intelligence.
Experience
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Stanford University, Palo Alto, California, USANov. 2019 – Mar. 2021
Postdoctoral Research Fellow
Advisor: Prof. Lei Xing
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NVIDIA, deep learning for medical imaging research group, Bethesda, Maryland, USAJul. 2018 – Oct. 2018
Applied Research Intern
Topic: Few-shot medical image segmentation
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Siemens Healthineers, Princeton, New Jersey, USAMar. 2017 – Jul. 2017
Research Intern
Topic: Body landmark detection via deep reinforcement learning
Selected Publications [Google Scholar]
2025
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SIB-MIL: Sparsity-Induced Bayesian Neural Network for Robust Multiple Instance Learning on Whole Slide Image Analysis
Yihang Chen, Tsai Hor Chan, Jianning Chen, Li Liang, Guosheng Yin, Lequan Yu.
IEEE Transactions on Medical Imaging (TMI), 2025. -
PASS: Probabilistic Agentic Supernet Sampling for Interpretable and Adaptive Chest X‑Ray Reasoning
Yushi Feng, Junye Du, Yingying Hong, Qifan Wang, Lequan Yu.
AAAI Conference on Artificial Intelligence (AAAI), 2026. -
FDP: A Frequency-Decomposition Preprocessing Pipeline for Unsupervised Anomaly Detection in Brain MRI
Hao Li, Zhenfeng Zhuang, Jingyu Lin, Yu Liu, Yifei Chen, Qiong Peng, Lequan Yu, Liansheng Wang.
AAAI Conference on Artificial Intelligence (AAAI), 2026. -
Knowledge-Guided Adaptation of Pathology Foundation Models Effectively Improves Cross-domain Generalization and Demographic Fairness
Yanyan Huang, Weiqin Zhao, Zhengyu Zhang, Yihang Chen, Yu Fu, Feng Wu, Yuming Jiang, Li Liang, Shujun Wang, Lequan Yu.
Nature Communications, 2025. -
Hist2Cell: Deciphering Fine-grained Cellular Architectures from Histology Images
Weiqin Zhao, Zhuo Liang, Xianjie Huang, Yuanhua Huang, Lequan Yu.
Cell Genomics, 2025. -
Feature Preserving Shrinkage on Bayesian Neural Networks via the R2D2 Prior
Tsai Hor Chan, Dora Yan Zhang, Guosheng Yin, Lequan Yu.
IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI), 2025. -
MedAgentBoard: Benchmarking Multi-Agent Collaboration with Conventional Methods for Diverse Medical Tasks
Yinghao Zhu, Ziyi He, Haoran Hu, Xiaochen Zheng, Xichen Zhang, Zixiang Wang, Junyi Gao, Liantao Ma, Lequan Yu.
Conference on Neural Information Processing Systems (NeurIPS), 2025. -
Amplifying Prominent Representations in Multimodal Learning via Variational Dirichlet Process
Tsai Hor Chan, Feng Wu, Yihang Chen, Guosheng Yin, Lequan Yu.
Conference on Neural Information Processing Systems (NeurIPS), 2025. -
Variational Polya Tree
Lu Xu, Tsai Hor Chan, Lequan Yu, Kwok Fai Lam, Guosheng Yin.
Conference on Neural Information Processing Systems (NeurIPS), 2025. -
Scaling Chest X-ray Foundation Models from Mixed Supervisions for Dense Prediction
Fuying Wang, Lequan Yu.
IEEE Transactions on Medical Imaging (TMI), 2025. -
MoST-IG: Morphology-Guided Spatial Transcriptomics Integration via Visual-Genomic Graph Optimal Transport
Liting Yu, Tao Ma, Weiqin Zhao, Zhuo Liang, Lequan Yu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2025. -
HyperPath: Knowledge-Guided Hyperbolic Semantic Hierarchy Modeling for WSI Analysis
Peixiang Huang, Yanyan Huang, Weiqin Zhao, Junjun He, Lequan Yu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2025. -
Bridging Radiological Images and Factors with Vision-Language Model for Accurate Diagnosis of Proliferative Hepatocellular Carcinoma
Yanyan Huang, Wanli Zhang, Peixiang Huang, Yu Fu, Ruimeng Yang, Lequan Yu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2025. -
Democratizing Large Language Model-Based Graph Data Augmentation via Latent Knowledge Graphs
Yushi Feng, Tsai Hor Chan, Guosheng Yin, Lequan Yu.
Neural Networks, 2025. -
CTPD: Cross-Modal Temporal Pattern Discovery for Enhanced Multimodal Electronic Health Records Analysis
Fuying Wang, Feng Wu, Yihan Tang, Lequan Yu.
Annual Meeting of the Association for Computational Linguistics (ACL), 2025. -
From Token to Rhythm: A Multi-Scale Approach for ECG-Language Pretraining
Fuying Wang, Jiacheng Xu, Lequan Yu.
International Conference on Machine Learning (ICML), 2025. -
Cross-Modal Alignment via Variational Copula Modelling
Feng Wu, Tsai Hor Chan, Fuying Wang, Guosheng Yin, Lequan Yu.
International Conference on Machine Learning (ICML), 2025. -
TAD-Graph: Enhancing Whole Slide Image Analysis via Task-Aware Subgraph Disentanglement
Fuying Wang, Jiayi Xin, Weiqin Zhao, Yuming Jiang, Maximus Yeung, Liansheng Wang, Lequan Yu.
IEEE Transactions on Medical Imaging (TMI), 2025. -
Large Images are Gaussians: High-Quality Large Image Representation with Levels of 2D Gaussian Splatting
Lingting Zhu, Guying Lin, Jinnan Chen, Xinjie Zhang, Zhenchao Jin, Zhao Wang, Lequan Yu.
AAAI Conference on Artificial Intelligence (AAAI), 2025. -
From Layers to States: A State Space Model Perspective to Deep Neural Network Layer Dynamics
Qinshuo Liu, Weiqin Zhao, Wei Huang, Yanwen Fang, Lequan Yu, Guodong Li.
International Conference on Learning Representations (ICLR), 2025.
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2024
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Aligning Knowledge Concepts to Whole Slide Images for Precise Histopathology Image Analysis
Weiqin Zhao, Ziyu Guo, Yinshuang Fan, Yuming Jiang, Maximus Yeung, Lequan Yu.
npj Digital Medicine, 2024. -
Free Lunch in Pathology Foundation Model: Task-specific Model Adaptation with Concept-Guided Feature Enhancement
Yanyan Huang, Weiqin Zhao, Yihang Chen, Yu Fu, Lequan Yu.
Conference on Neural Information Processing Systems (NeurIPS), 2024. -
Unleash the Power of State Space Model for Whole Slide Image with Local Aware Scanning and Importance Resampling
Yanyan Huang, Weiqin Zhao, Yu Fu, Lingting Zhu, Lequan Yu.
IEEE Transactions on Medical Imaging (TMI), 2024. -
Multi-sensor Learning Enables Information Transfer across Different Sensory Data and Augments Multi-modality Imaging
Lingting Zhu, Yizheng Chen, Lianli Liu, Lei Xing, Lequan Yu.
IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI), 2024. -
HERGen: Elevating Radiology Report Generation with Longitudinal Data
Fuying Wang, Shenghui Du, Lequan Yu.
European Conference on Computer Vision (ECCV), 2024. -
cDP-MIL: Robust Multiple Instance Learning via Cascaded Dirichlet Process
Yihang Chen, Tsai Hor Chan, Guosheng Yin, Yuming Jiang, Lequan Yu.
European Conference on Computer Vision (ECCV), 2024. -
Multi-task Heterogeneous Graph Learning on Electronic Health Records
Tsai Hor Chan, Guosheng Yin, Kyongtae Bae, Lequan Yu.
Neural Networks, 2024. -
Swin-UMamba: Mamba-based UNet with ImageNet-based pretraining
Jiarun Liu, Hao Yang, Hong-Yu Zhou, Yan Xi, Lequan Yu, Yizhou Yu, Yong Liang, Guangming Shi, Shaoting Zhang, Hairong Zheng, Shanshan Wang.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024. -
ORCGT: Ollivier-Ricci Curvature-based Graph Model for Lung STAS Prediction
Min Cen, Zheng Wang, Zhenfeng Zhuang, Hong Zhang, Dan Su, Zhen Bao, Weiwei Wei, Baptiste Magnier, Lequan Yu, Liansheng Wang.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024. -
Advancing H&E-to-IHC Virtual Staining with Task-Specific Domain Knowledge for HER2 Scoring
Qiong Peng, Weiping Lin, Yihuang Hu, Ailisi Bao, Chenyu Lian, Weiwei Wei, Meng Yue, Jingxin Liu, Lequan Yu, Liansheng Wang.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024. -
L2B: Learning to Bootstrap Robust Models for Combating Label Noise
Yuyin Zhou, Xianhang Li, Fengze Liu, Qingyue Wei, Xuxi Chen, Lequan Yu, Cihang Xie, Matthew P. Lungren, Lei Xing.
IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2024. -
A Dual Enrichment Synergistic Strategy to Handle Data Heterogeneity for Domain Incremental Cardiac
Segmentation
Kang Li, Yu Zhu, Lequan Yu, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2024. -
Boosting Multiple Instance Learning Models for Whole Slide Image Classification: A Model-agnostic Framework Based on Counterfactual Inference
Weiping Lin, Zhenfeng Zhuang, Lequan Yu, Liansheng Wang.
AAAI Conference on Artificial Intelligence (AAAI), 2024. -
Memory-Efficient Prompt Tuning for Incremental Histopathology Classification
Yu Zhu, Kang Li, Lequan Yu, Pheng-Ann Heng.
AAAI Conference on Artificial Intelligence (AAAI), 2024.
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2023
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Adaptive Uncertainty Estimation via High-Dimensional Testing on Latent Representations
Tsai Hor Chan, Kin Wai Lau, Jiajun Shen, Guosheng Yin, Lequan Yu.
Conference on Neural Information Processing Systems (NeurIPS), 2023. -
IDRNet: Intervention-Driven Relation Network for Semantic Segmentation
Zhenchao Jin, Xiaowei Hu, Lingting Zhu, Luchuan Song, Li Yuan, Lequan Yu.
Conference on Neural Information Processing Systems (NeurIPS), 2023. -
ConSlide: Asynchronous Hierarchical Interaction Transformer with Breakup-Reorganize Rehearsal for Continual Whole Slide Image Analysis
Yanyan Huang, Weiqin Zhao, Shujun Wang, Yu Fu, Yuming Jiang, Lequan Yu.
International Conference on Computer Vision (ICCV), 2023. -
HIGT: Hierarchical Interaction Graph-Transformer for Whole Slide Image Analysis
Ziyu Guo, Weiqin Zhao, Shujun Wang, Lequan Yu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2023. -
Make-A-Volume: Leveraging Latent Diffusion Models for Cross-Modality 3D Brain MRI Synthesis
Lingting Zhu, Zeyue Xue, Zhenchao Jin, Xian Liu, Jingzhen He, Ziwei Liu, Lequan Yu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2023. -
Adaptive Region-Specific Loss for Improved Medical Image Segmentation
Yizheng Chen, Lequan Yu, Jen-Yeu Wang, Neil Panjwani, Jean-Pierre Obeid, Wu Liu, Lianli Liu, Nataliya Kovalchuk, Michael Francis Gensheimer, Lucas Kas Vitzthum, Beth M Beadle, Daniel T Chang, Quynh-Thu Le, Bin Han, Lei Xing.
IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI), 2023. -
Shared-specific Feature Learning with Bottleneck Fusion Transformer for Multi-modal Whole Slide Image Analysis
Zhihua Wang, Lequan Yu, Xin Ding, Xuehong Liao, Liansheng Wang.
IEEE Transactions on Medical Imaging (TMI), 2023. -
RECIST-induced Reliable Learning: Geometry-driven Label Propagation for Universal Lesion Segmentation
Lianyu Zhou, Lequan Yu, Liansheng Wang.
IEEE Transactions on Medical Imaging (TMI), 2023. -
Transformer-based Multimodal Fusion for Survival Prediction by Integrating Whole Slide Images, Clinical, and Genomic Data
Yihang Chen, Weiqin Zhao, Lequan Yu.
IEEE International Symposium on Biomedical Imaging (ISBI), 2023. -
Histopathology Whole Slide Image Analysis with Heterogeneous Graph Representation Learning
Tsai Hor Chan, Fernando Julio Cendra, Lan Ma, Guosheng Yin, Lequan Yu.
IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2023. -
Taming Diffusion Models for Audio-Driven Co-Speech Gesture Generation
Lingting Zhu, Xian Liu, Xuanyu Liu, Rui Qian, Ziwei Liu, Lequan Yu.
IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2023. -
MagicNet: Semi-Supervised Multi-Organ Segmentation via Magic-Cube Partition and Recovery
Duowen Chen, Yunhao Bai, Wei Shen, Qingli Li, Lequan Yu, Yan Wang.
IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2023. -
Hybrid Graph Convolutional Network with Online Masked Autoencoder for Robust Multimodal Cancer Survival Prediction
Wentai Hou, Chengxuan Lin, Lequan Yu, Jing Qin, Rongshan Yu, Liansheng Wang.
IEEE Transactions on Medical Imaging (TMI), 2023. -
MulGT: Multi-task Graph-Transformer with Task-aware Knowledge Injection and Domain Knowledge-driven Pooling for Whole Slide Image Analysis
Weiqin Zhao, Shujun Wang, Maximus Yeung, Tianye Niu, Lequan Yu.
AAAI Conference on Artificial Intelligence (AAAI), 2023.
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2022
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Leveraging data-driven self-consistency for high-fidelity gene expression recovery
Md Tauhidul Islam, Jen-Yeu Wang, Hongyi Ren, Xiaomeng Li, Masoud Badiei Khuzani, Shengtian Sang, Lequan Yu, Liyue Shen, Wei Zhao, Lei Xing.
Nature Communications, 2022. -
Data Discernment for Affordable Training in Medical Image Segmentation
Youyi Song, Lequan Yu, Baiying Lei, Kup-Sze Choi, Jing Qin.
IEEE Transactions on Medical Imaging (TMI), 2022. -
MuRCL: Multi-instance Reinforcement Contrastive Learning for Whole Slide Image Classification
Zhonghang Zhu, Lequan Yu, Wei Wu, Rongshan Yu, Defu Zhang, Liansheng Wang.
IEEE Transactions on Medical Imaging (TMI), 2022. -
Multi-Granularity Cross-modal Alignment for Generalized Medical Visual Representation Learning
Fuying Wang, Yuyin Zhou, Shujun Wang, Varut Vardhanabhuti, Lequan Yu.
Conference on Neural Information Processing Systems (NeurIPS), 2022. -
MCIBI++: Soft Mining Contextual Information Beyond Image for Semantic Segmentation
Zhenchao Jin, Dongdong Yu, Zehuan Yuan, Lequan Yu.
IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI), 2022. -
You Should Look at All Objects
Zhenchao Jin, Dongdong Yu, Luchuan Song, Zehuan Yuan, Lequan Yu.
European Conference on Computer Vision (ECCV), 2022. -
Domain-incremental Cardiac Image Segmentation with Style-oriented Replay and Domain-sensitive Feature Whitening
Kang Li, Lequan Yu, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2022. -
NestedFormer: Nested Modality-Aware Transformer for Brain Tumor Segmentation
Zhaohu Xing, Lequan Yu, Liang Wan, Tong Han, Lei Zhu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2022. -
Joint Prediction of Meningioma Grade and Brain Invasion via Task-Aware Contrastive Learning
Tianling Liu, Wennan Liu, Lequan Yu, Liang Wan, Tong Han, Lei Zhu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2022. -
Spatial-hierarchical Graph Neural Network with Dynamic Structure Learning for Histological Image Classification
Wentai Hou, Helong Huang, Qiong Peng, Rongshan Yu, Lequan Yu, Liansheng Wang.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2022. -
Reinforcement Learning Driven Intra-modal and Inter-modal Representation Learning for 3D Medical Image Classification
Zhonghang Zhu, Liansheng Wang, Baptiste Magnier, Lei Zhu, Defu Zhang, Lequan Yu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2022. -
CD²-pFed: Cyclic Distillation-guided Channel Decoupling for Model Personalization in Federated Learning
Yiqing Shen, Yuyin Zhou, Lequan Yu.
IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 2022. -
H²-MIL: Exploring Hierarchical Representation with Heterogeneous Multiple Instance Learning for Whole Slide Image Analysis
Wentai Hou, Lequan Yu, Chengxuan Lin, Helong Huang, Rongshan Yu, Jing Qin, Liansheng Wang.
AAAI Conference on Artificial Intelligence (AAAI), 2022. -
Lymph Node Metastasis Prediction from Whole Slide Images with Transformer-guided Multi-instance Learning and Knowledge Transfer
Zhihua Wang, Lequan Yu, Xin Ding, Xuehong Liao, Liansheng Wang.
IEEE Transactions on Medical Imaging (TMI), 2022. -
Novel-view X-ray Projection Synthesis through Geometry-integrated Deep Learning
Liyue Shen, Lequan Yu, Wei Zhao, John Pauly, Lei Xing.
Medical Image Analysis (MedIA), 2022. -
Towards Reliable Cardiac Image Segmentation: Assessing Image-level and Pixel-level Segmentation Quality via Self-reflective References
Kang Li, Lequan Yu, Pheng-Ann Heng.
Medical Image Analysis (MedIA), 2022. -
Robust Medical Image Classification from Noisy Labeled Data with Global and Local Representation Guided Co-training
Cheng Xue, Lequan Yu, Pengfei Chen, Qi Dou, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2022.
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2021
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Metal Artifact Reduction in 2D CT Images with Self-supervised Cross-domain Learning
Lequan Yu, Zhicheng Zhang, Xiaomeng Li, Hongyi Ren, Wei Zhao, Lei Xing.
Physics in Medicine & Biology (PMB), 2021. -
TransCT: Dual-path Transformer for Low Dose Computed Tomography
Zhicheng Zhang, Lequan Yu, Xiaokun Liang, Wei Zhao, Lei Xing.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2021.[code]
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Selective Learning from External Data for CT Image Segmentation
Youyi Song, Lequan Yu, Baiying Lei, Kup-Sze Choi, Jing Qin.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2021. Student Travel Award[code]
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Deep Neural Network with Consistency Regularization of Multi-Output Channels for Improved Tumor Detection and Delineation
Hyunseok Seo, Lequan Yu, Hongyi Ren, Xiaomeng Li, Liyue Shen, Lei Xing.
IEEE Transactions on Medical Imaging (TMI), 2021. -
Rotation-oriented Collaborative Self-supervised Learning for Retinal Disease Diagnosis
Xiaomeng Li, Xiaowei Hu, Xiaojuan Qi, Lequan Yu, Wei Zhao, Pheng-Ann Heng, Lei Xing.
IEEE Transactions on Medical Imaging (TMI), 2021.[code]
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MR to ultrasound image registration with segmentation-based learning for HDR prostate brachytherapy
Yizheng Chen, Lei Xing, Lequan Yu, Wu Liu, Benjamin P Fahimian, Thomas Niedermayr, Hilary Bagshaw, Mark K Buyyounouski, Bin Han.
Medical Physics, 2021. -
Modularized Data-Driven Reconstruction Framework for Non-ideal Focal Spot Effect Elimination in Computed Tomography
Zhicheng Zhang, Lequan Yu, Wei Zhao, Lei Xing.
Medical Physics, 2021. -
Deep Sinogram Completion with Image Prior for Metal Artifact Reduction in CT Images
Lequan Yu, Zhicheng Zhang, Xiaomeng Li, Lei Xing.
IEEE Transactions on Medical Imaging (TMI), 2021.
2020
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Dual-Teacher++: Exploiting Intra-domain and Inter-domain Knowledge with Reliable Transfer for Cardiac Segmentation
Kang Li, Shujun Wang, Lequan Yu†, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2020. -
Automatic intraprostatic lesion segmentation in multiparametric magnetic resonance images with proposed multiple branch UNet
Yizheng Chen, Lei Xing, Lequan Yu, Hilary P. Bagshaw, Mark K. Buyyounouski, Bin Han.
Medical Physics, 2020. -
Learning from Extrinsic and Intrinsic Supervisions for Domain Generalization
Shujun Wang, Lequan Yu†, Caizi Li, Chi-Wing Fu, Pheng-Ann Heng.
European Conference on Computer Vision (ECCV), 2020.[code]
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DoFE: Domain-oriented Feature Embedding for Generalizable Fundus Image Segmentation on Unseen Datasets
Shujun Wang, Lequan Yu†, Kang Li, Xin Yang, Chi-Wing Fu, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2020.[code]
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Deep Mining External Imperfect Data for Chest X-ray Diseases Screening
Luyang Luo*, Lequan Yu*, Hao Chen, Quande Liu, Xi Wang, Jiaqi Xu, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2020. -
Semi-supervised Medical Image Classication with Relation-driven Self-ensembling Model
Quande Liu, Lequan Yu†, Luyang Luo, Qi Dou, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2020.[code]
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Towards Cross-modality Medical Image Segmentation with Online Mutual Knowledge Distillation
Kang Li, Lequan Yu†, Shujun Wang, and Pheng-Ann Heng.
AAAI Conference on Artificial Intelligence (AAAI), 2020. -
Robust Medical Image Segmentation from Non-expert Annotations with Tri-network
Tianwei Zhang*, Lequan Yu*, Na Hu, Su Lv, Shi Gu.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2020. -
Dual-Teacher: Integrating Intra-domain and Inter-domain Teachers for Annotation-efficient Cardiac Segmentation
Kang Li, Shujun Wang, Lequan Yu†, Pheng-Ann Heng.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2020. -
Difficulty-aware Meta-learning for Rare Disease Diagnosis
Xiaomeng Li, Lequan Yu, Yueming Jin, Chi-Wing Fu, Lei Xing, Pheng-Ann Heng.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2020. -
Unsupervised Detection of Distinctive Regions on 3D Shapes
Xianzhi Li, Lequan Yu, Chi-Wing Fu, Daniel Cohen-Or, Pheng-Ann Heng.
ACM Transactions on Graphics (ACM TOG), 2020.[code]
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Transformation-consistent Self-ensembling Model for Semi-supervised Medical Image Segmentation
Xiaomeng Li, Lequan Yu, Hao Chen, Chi-Wing Fu, Lei Xing, Pheng-Ann Heng.
IEEE Transaction on Neural Network and Learning System (TNNLS), 2020.[code]
Before 2020
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Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentation
Lequan Yu, Shujun Wang, Xiaomeng Li, Chi-Wing Fu, and Pheng-Ann Heng.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2019.[code]
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CANet: Cross-disease Attention Network for Joint Diabetic Retinopathy and Diabetic Macular Edema Grading
Xiaomeng Li, Xiaowei Hu, Lequan Yu, Lei Zhu, Chi-Wing Fu, and Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2019.[code]
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RMDL: Recalibrated multi-instance deep learning for whole slide gastric image classification
Shujun Wang, Yaxi Zhu, Lequan Yu, Hao Chen, Huangjing Lin, Xiangbo Wan, Xinjuan Fan, and Pheng-Ann Heng.
Medical Image Analysis (MedIA), 2019. -
Patch-based Output Space Adversarial Learning for Joint Optic Disc and Cup Segmentation
Shujun Wang, Lequan Yu, Xin Yang, Chi-Wing Fu, and Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2019. Ranked 1st place in REFUGE 2018 Optic Disc and Cup Segmentation Challenge[project]
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PU-Net: Point Cloud Upsampling Network
Lequan Yu, Xianzhi Li, Chi-Wing Fu, Daniel Cohen-Or, Pheng-Ann Heng.
IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 2018. -
EC-Net: an Edge-aware Point set Consolidation Network
Lequan Yu, Xianzhi Li, Chi-Wing Fu, Daniel Cohen-Or, Pheng-Ann Heng.
European Conference on Computer Vision (ECCV), 2018. -
Towards Automated Semantic Segmentation in Prenatal Volumetric Ultrasound
Xin Yang, Lequan Yu, Shengli Li, Huaxuan Wen, Dandan Luo, Cheng Bian, Jing Qin, Dong Ni, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2018.[project]
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Volumetric ConvNets with Mixed Residual Connections for Automated Prostate Segmentation from 3D MR Images
Lequan Yu, Xin Yang, Hao Chen, Jing Qin, Pheng-Ann Heng.
AAAI Conference on Artificial Intelligence (AAAI), 2017. [Oral Presentation] Ranked 1st on Prostate MR Image Segmentation (PROMISE12) leaderboard, until Jan. 2018. -
Automatic 3D Cardiovascular MR Segmentation with Densely-Connected Volumetric ConvNets
Lequan Yu, Jie-Zhi Cheng, Qi Dou, Xin Yang, Hao Chen, Jing Qin, Pheng-Ann Heng.
Medical Image Computing and Computer Assisted Intervention (MICCAI), 2017. -
Automated Melanoma Recognition in Dermoscopy Images via Very Deep Residual Networks
Lequan Yu, Hao Chen, Qi Dou, Jing Qin, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2017. ESI Highly Cited Paper Ranked 1st place in Skin Lesion Analysis Towards Melanoma Detection Challenge (ISIC 2016)[project] [code] [challenge website]
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Integrating Online and Offline 3D Deep Learning for Automated Polyp Detection in Colonoscopy Videos
Lequan Yu, Hao Chen, Qi Dou, Jing Qin, Pheng-Ann Heng.
IEEE Journal of Biomedical and Health Informatics (JBHI), 2017. -
3D Deeply Supervised Network for Automated Segmentation of Volumetric Medical Images
Qi Dou, Lequan Yu, Hao Chen, Yueming Jin, Xin Yang, Jing Qin, Pheng-Ann Heng.
Medical Image Analysis (MedIA), 2017.
ESI Highly Cited Paper MedIA-MICCAI'17 Best Paper Award[code]
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3D FractalNet: Dense Volumetric Segmentation for Cardiovascular MRI Volumes
Lequan Yu, Xin Yang, Jing Qin, Pheng-Ann Heng.
MICCAI Workshop on Whole-Heart and Great Vessel Segmentation from 3D Cardiovascular MRI in Congenital Heart Disease, 2016. Ranked 1st place in Whole-Heart and Great Vessel Segmentation Challenge -
Automatic Detection of Cerebral Microbleeds from MR Images via 3D Convolutional Neural Networks
Qi Dou*, Hao Chen*, Lequan Yu, Lei Zhao, Jing Qin, Defeng Wang, Vincent CT Mok, Lin Shi, Pheng-Ann Heng.
IEEE Transactions on Medical Imaging (TMI), 2016. ESI Highly Cited Paper[project]
Students
Current Students:| Zhenchao Jin (MPhil at USTC)(PhD Student, 2022-) |
| Zhuo Liang (BSc at HKU)(PhD Student, 2022-)(HKU-PS) |
| Yihang Chen (BSc at RUC)(PhD Student, 2023-) |
| Yanyan Huang (MPhil at ZJU)(PhD Student, 2023-) |
| Feng Wu (MPhil at ZJU)(PhD Student, 2023-) |
| Jiacheng Xu (BSc at HKU)(PhD Student, 2023-)(HKPF) |
| Liting Yu (BSc at XJTU)(PhD Student, 2023-) |
| Yushi Feng (BSc at HKU)(PhD Student, 2024-) |
| Peixiang Huang (MPhil at PKU)(PhD Student, 2024-) |
| Tao Ma (MPhil at PKU)(PhD Student, 2024-) |
| Ziyan Xiao (BASc at HKU)(PhD Student, 2024-)(HKPF) |
| Ruiyang Zhang (MSc at NUS)(PhD Student, 2024-) |
| Ziyi He (BSc at HKU)(PhD Student, 2025-)(HKPF) |
| Kailing Wang (BEng at SJTU)(PhD Student, 2025-)(HKUPS) |
| Wenting Zhang (BA at Cambridge)(PhD Student, 2025-) |
| Yinghao Zhu (MPhil at Beihang)(PhD Student, 2025-) |
Co-supervised Students:
| Xuanyu Liu (Mphil at SUSTech)(PhD Student, 2021-)(w/ K.C. Yuen) |
| Yan Miao (MPhil at McGill)(PhD Student, 2022-)(HKPF) (w/ Wai-Kay Seto) |
| Pei Cai (MPhil at NTU)(PhD Student, 2023-) (w/ Jianpan Huang) |
Intern/RA/Postdoc:
| Liang Peng (PhD at UESTC)(Postdoc, 2024-) |
| Qiang Ma (MPhil at UESTC)(RA, 2025-) |
| Lanyu Zhang (BEng at SJTU, Master student at HKU)(RA, 2025-) |
| Joris Mentink (Master student at Eindhoven University of Technology)(Visiting student, 2025-) |
| Qingyang Ma (UG student at SYSU)(RA, 2025-) |
Alumni:
| Howard Tsai Hor Chan (2025 PhD)(now, Postdoc at UPenn) |
| Fuying Wang (2025 PhD)(now, Postdoc at Stanford) |
| Weiqin Zhao (2025 PhD)(now, Postdoc at Technical University Dresden) |
| Lingting Zhu (2025 PhD)(now, Senior Researcher at Tencent LightSpeed Studios) |
| Jiayi Xin (2024 Undergraduate Intern) (BASc at HKU --> PhD at UPenn) |
| Ziyan Xiao (2024 Undergraduate Intern) (BASc at HKU --> PhD at HKU) |
| Yushi Feng (2024 Undergraduate Intern) (BSc at HKU --> PhD at HKU) |
| Jiacheng Xu (2023 Undergraduate Intern) (BSc at HKU --> PhD at HKU) |
| Wing Kwan Pang (2023 Undergraduate Intern) (BSc at HKU --> MPhil at HKU) |
| Xi Zheng (2022 Summer Intern) (BSc at XJTU --> IS PhD at UW) |
| Tengfei Cui (2022 Summer Intern) (BSc at XJ-Liverpool --> MS Biostatistics at UW) |
| Yiqing Shen (2021 Summer Intern) (BSc at SJTU --> CS PhD at JHU) |
| Ruichen Luo (2021 Summer Intern) (BEng at ZJU --> ECE PhD at UMN) |
| Xiaoyu Zhang (2021 Summer Intern) (BEng at ZJU --> MCDS at CMU) |
| Zeqi Xiao (2021 Summer Intern) (BEng at ZJU --> PhD at NTU) |
| Yijun Yang (2021 Summer Intern) (BEng at SDU --> PhD at HKUST-GZ) |
| Kang Li (Ph.D. at CUHK) (now, Asst. Prof. at UESTC) |
Recent Talks & Presentations
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Leveraging Deep Learning in Computational Pathology: from Single-modal to Multi-modal Analysis
at The Third Affiliated Hospital of Sun Yat-sen University, April 2024.
at Zhejiang Lab, Hangzhou, July 2023.
at Shanghai AI Lab, Shanghai, July 2023.
at Computational Health seminar, Helmholtz AI, German, July 2023.
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Learning generalized medical visual representation from accompanied medical reports
at MICS online seminar, April 2023.
at Department of Biomedical Engineering, SZU, April 2023.
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Medical Image Analysis and Reconstruction with Data-efficient Learning
at VALSE 2022 workshop "医学数据分析中的深度学习方法", August 2022.
at Beihang University, May 2022.
at Zhejiang University, May 2022.
at 海峡两岸暨港澳精准医学青年博士论坛, November 2021.
at 中国医师协会第十五次放射医师年会, October 2021.
at Nanjing University of Information Science and Technology, October 2021.
at Department of Electrical and Electronic Engineering, HKU, September 2021.
at MICS 2021, July 2021.
at Data Science and Computational Statistics Seminar, University of Birmingham, February 2021. -
AI for Medical Imaging: Applications and Beyond
at AI and Big Data Research for Health Improvement Symposium, Institute of Data Science, HKU, August 2022.
at Mini-Symposium on Interdisciplinary Research, Faculty of Science, HKU, January 2022.
at School of Biomedical Sciences, HKU, December 2021. -
The Applications of Transformer in Volumetric Segmentation and Low Dose CT
at VALSE Webinar, October 2022.
Honors & Awards
| The world’s top 1% scholars ranked by Clarivate Analytics, 2023 |
| MICCAI 2023 Young Scientist Publication Impact Award Runner-up, 2023 |
| 国家教育部高等学校科学研究优秀成果奖(科学技术), 自然科学二等奖 (排名: 4/5), 2022 |
| Ranked Top 2% of Scientists on Stanford List, 2022 and 2023 |
| the World's First List of Top 150 Chinese Young Scholars in Artificial Intelligence, 2022 |
| Rising Star of Science Award by Research.com, 2022 |
| IEEE TMI Distinguished Reviewer Platinum Level, 2022 and 2023 |
| IEEE TMI Distinguished Reviewer Silver Level, 2021 |
| CUHK Young Scholars Thesis Award 2019 |
| Young Scientist Award Short-listed, Hong Kong Institution of Science, 2019 |
| Teaching Assistant of Merit, 2018 |
| MedIA-MICCAI'17 Best Paper Award, 2017 |
| AAAI Scholarship, San Fransisco, USA, 2017 |
| Champion, Optic Disc&Cup Segmentation on Retinal Fundus Images (REFUGE 2018) |
| Champion, Whole-Heart and Great Vessel Segmentation (HVSMR 2016) |
| Champion, Skin Lesion Analysis Towards Melanoma Detection Challenge (ISIC 2016) |
| Champion, Prostate MR Image Segmentation 2012 (PROMISE12, until 2018 Jan.) |
| National Scholarship in China (1.8%), 2012-2014 |
| He Zhijun Scholarship (1/300+, Highest Honor in College of Computer Science, Zhejiang University), 2014 |
| Kwanjeong Educational Foundation Scholarship, 2012-2014 |
| Meritorious Winner, Interdisciplinary Contest in Modeling (ICM), Consortium for Mathematics and Its Application, 2014 |
| The Outstanding Undergraduate Award (Awarded by CCF, 100 undergraduates every year in China), 2014 |
| Outstanding Graduates of Zhejiang University, 2015 |
Professional Activities
Area Chair of Medical Image Computing and Computer Assisted Intervention (MICCAI’22-24)
Senior Program Committee of AAAI Conference on Artificial Intelligence (AAAI’22)
Senior Program Committee of International Joint Conference on Artificial Intelligence (IJCAI’21)
Co-organizer of ICCV workshop on Computer Vision for Automated Medical Diagnosis (ICCV'21 and ICCV'23)
IEEE Conference on Computer Vision and Pattern Recognition (CVPR’19-22)
PC of AAAI Conference on Artificial Intelligence (AAAI’20-21)
IEEE International Conference on Computer Vision (ICCV’21, ICCV'19)
Medical Image Computing and Computer Assisted Intervention (MICCAI’18-21)
IEEE Winter Conference on Applications of Computer Vision (WACV’20-21)
Medical Imaging with Deep Learning (MIDL’21)
SIGGRAPH 2020
European Conference on Computer Vision (ECCV’20)
Asian Conference on Computer Vision (ACCV’20)
Nature Machine Intelligence
Nature Computational Science
Nature Communications
IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI)
International Journal of Computer Vision (IJCV)
Medical Image Analysis (MedIA)
IEEE Transactions on Medical Imaging (TMI)
IEEE Transactions on Image Processing (TIP)
IEEE Transactions on Biomedical Engineering (TBME)
IEEE Transactions on Neural Networks and Learning Systems (TNNLS)
IEEE Transactions on Automation Science and Engineering (TASE)
IEEE Transactions on Artificial Intelligence (TAI)
IEEE Transactions on Big Data (TBD)
IEEE Transactions on Dependable and Secure Computing
IEEE Journal of Biomedical and Health Informatics (JBHI)
IEEE Robotics and Automation Letters (RA-L)
Teaching
| 2023&2024 Spring | STAT8021 Big Data Analytics |
| 2023&2024 Spring | STAT8307 Natural Language Processing and Text Analysis |
| 2022&2023 Fall | STAT3612 Statistical Machine Learning |
| 2022 Fall | BIOF1001 Introduction to Biomedical Data Science (guest lecture) |
| 2022 Spring | APAI4011/STAT4011 Natural Language Processing |






