Longevity Escape Velocity Foundation

In a nutshell: the last mouse died on February 12th, and the final survival curves are attached. As I noted in the last update, we have what I think we can call a "qualified win" wirth this study…

Just four mice have made it to 2025 (yeah, I'm 55 hours optimistic there...), all of them male, and once they die I will launch into the next phase of updates, which will consist of lots of statistical analyses of the survival curves, followed by various reports on our healthspan data. For now, though, I will continue the habit of highlighting some of the qualitative impressions that the survival curves are telling us.

The milestone we have hit this time is that all 20 groups (10 male and 10 female) have now reached their last "cull point", i.e. the point where only eight mice of the original 50 are alive and we sacrifice two of them to store various tissues, as well as doing a lot of the non-invasive measurements on the others...

We're getting fairly near to the end of the study - but how near, we certainly can't yet say. Six of the 20 treatment groups, two male and four female, are now extinct, but the all-treatment groups of both sexes are still at 25% survival at over 35 months of age, which gives hope that the longest-lived mouse in the entire study will turn out to be fairly impressive...