Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by eczematous lesions and intense pruritus, posing a significant public health challenge. Conventional therapies, primarily based on corticosteroids and immunosuppressants, have limited efficacy and are associated with significant adverse effects. The therapeutic use of mesenchymal stem cells (MSCs) or their secretome, including extracellular vesicles (VEs), has shown promising immunomodulatory effects in the treatmen...

INTRODUCTION: Oral Squamous Cell Carcinoma (OSCC) remains a significant public health concern. Despite advances in treatments, including surgery, and chemotherapy, choices remain limited, underscoring the need for innovative therapeutic strategies. Developing new drugs is both costly and time-intensive. Drug repurposing offers a compelling solution by leveraging existing, well-characterized medications that are already approved and toxicologically safe. OBJECTIVE: Identify promising candidate...

INTRODUCTION: Leishmaniasis is an infectious disease of global importance, characterized by ulcerative lesions with raised borders and exacerbated inflammation. The main first-line therapy, pentavalent antimony (Sb⁵⁺), has limited efficacy, with frequent treatment failure rates. In this context, transcriptomic analyses have emerged as promising tools for identifying biomarkers with predictive potential for treatment response. OBJECTIVE: This study aimed to compare transcriptional signatures f...

This study aims to analyze inclusive pedagogical practices developed in the early grades of elementary school, from the perspective of teachers working with students in the Special Education target group at a municipal public school in Salvador, Bahia. The research, which uses a qualitative and descriptive approach, combines a literature review with a case study, using legal documents and authors in the field of school inclusion as theoretical frameworks. Data collection was conducted throug...

This dissertation analyzes the emergence of the Igreja Cristã Contemporânea (ICC) in Salvador, investigating how LGBTQIAPN+ subjects, historically marginalized by traditional evangelical Christianity, appropriate Pentecostal religious grammar to construct new forms of religious belonging. In a context where Pentecostalism is frequently associated with conservative discourses and the exclusion of sexual and gender dissidence, the ICC stands as a unique empirical case by articulating an i...

This work presents the agencements (enactments/activations) of Women's Circles in Brazil, a non-institutional movement of feminine spirituality organized by women and for women, predominantly cisgender, white, and middle-class. However, the research, conducted in Salvador and its metropolitan area, identified a more diverse movement, with the presence and protagonism of Black women and openness to the participation of trans women. To understand these dynamics, I carried out fieldwor...

This study addresses experiential marketing as a strategy adopted by shopping centers, focusing on the case of Shopping Barra in Salvador, Brazil. It is a qualitative case study that seeks to understand how institutional and promotional practices are structured to create emotional bonds with consumers and promote loyalty. The investigation is based on the understanding that contemporary consumption goes beyond a functional logic, valuing sensory, emotional, and symbolic experiences that ...

This study analyzes the evolution of energy consumption in Brazil’s road transport sector and examines how public policies for biofuels and electrification shape its energy transition. Using data from the National Energy Balance, reports from the Energy Research Company and specialized literature, the results show that the sector remains highly dependent on diesel, especially in freight transport. However, gradual diversification is observed, driven by ethanol in light-duty vehicles, biodie...

This study evaluates the characteristics of different management models for logistics processes within the Brazilian Federal Revenue Service (RFB) and their contributions to overall logistics performance, aiming to support the development of a standardized national model. In recent years, the RFB has faced a shrinking workforce due to retirements and the absence of new public recruitment, combined with the need to specialize knowledge to optimize tasks and improve service quality, as well as ...

This study investigates capoeira as an ancestral game and a social technology applied to the inclusion of neurodivergent people within the context of civil society organizations in Salvador, Bahia. The general objective of the study is to promote the development of autonomy, independence, and social inclusion of neurodivergent people through the practice of capoeira in Civil Society Organizations (CSOs) in the municipality of Salvador, Bahia. As specific objectives, the study seeks to i...

This study addresses the disclosure of information on climate change, aiming to investigate the relationship between the factors influencing the disclosure of information on climate risks by companies listed on the BM&FBovespa. To this end, the content analysis technique was used to measure the level of disclosure. The sample was extracted from the population of companies listed on the BM&FBovespa that disclose sustainability reports, in accordance with the Global Reporting Initiative (GRI) g...

The impossibility of fulfilling cumulative and equivalent duties in the practice of medicine in emergency and urgent care services became particularly evident during the COVID-19 pandemic, highlighting challenges related to medical criminal liability in such circumstances. This study arises in the absence of specific legal provisions and doctrinal uncertainty on the topic, proposing to develop an appropriate dogmatic-criminal approach to solve this problem. The general objective is to seek a ...

This study analyzes the manifestation of religious racism within the Brazilian prison system, with a specific focus on the Salvador Women’s Penal Complex (Bahia). The research is anchored in the premise that, despite the fundamental guarantee of freedom of belief and worship provided by the 1988 Federal Constitution, its application is selective and shaped by historical structures of racial discrimination. The work traces the legal trajectory of Brazilian constitutionalism, demonstrating how,...

Testimonial narratives are studied by literary critics considering personal records of experiences of state violence, where the individual traumatic experience illustrates a broader context, mainly one in which the narrative given by the victims (of dictatorships, genocides, wars, etc.) is suppressed by the official historiographical and cultural narrative. In this work, through the work of the American rapper Kendrick Lamar, we seek to understand hip-hop as an artistic-cultural movement of r...

The PPI Project Database covers private participation in infrastructure in developing countries. The database records details of all projects owned or managed by private companies in 1984-97 in the water, energy, transport, and telecommunications sectors. This Note focuses on private water and sewerage projects that reached financial closure between 1990 and 1997 and surveys regional trends, type of private participation, project size, and top sponsors and operators. See box 1 for an explana...

This Note, which draws on the World Bank’s Private Participation in Infrastructure (PPI) Project Database, analyzes the patterns in airport projects with private participation that reached financial closure in 1990–98 (box 1). The database covers projects with potential natural monopoly elements: construction or rehabilitation and operation of facilities required for takeoff and landing, traffic control towers, and passenger and cargo terminals. Separate concessions for shopping areas, restau...

During the 1990s developing countries increasingly turned to the private sector for construction, management, and maintenance of toll roads. Between 1990 and 1999, US$61 billion of private investment was committed to 279 projects in 26 developing countries, comprising 34,369 kilometers of toll highways, bridges, and tunnels. 1 This Note analyzes the main trends in private participation in toll roads in developing countries using figures from the World Bank’s Private Participation in Infrastr...