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Contact Info:
- Atlanta, GA
- ORCID
- Google Scholar
- ResearchGate
- About
- Research
- Publications
- Experience
June 2025: Paper is accepted for presentation at ESSERC 2025!
May 2025: Dr. Ibrahim will serve as a TPC member for ASP-DAC 2026!
February 2025: Dr. Ibrahim will serve as a TPC member for ICCAD 2025.
February 2025: Our work on embodied AI acceleration accepted to ASPLOS.
January 2025: Dr. Ibrahim will serve as a TPC member for ASAP 2025.
September 2024: Dr. Ibrahim will serve as a TPC member for DATE 2025.
August 2024: Our journal paper is accepted for publication in IEEE TCASAI!
July 2024: Dr. Ibrahim will serve as a TPC member for ASP-DAC 2025.
May 2024: Our proposal for a special session at ESWeek 2024 has been accepted! The session is entitled: "Neuro-Symbolic Architecture Meets LLMs: A Memory-Centric Perspective".
April 2024: Dr. Ibrahim will serve as a TPC member for ICCAD 2024.
November 2023: Two papers accepted for presentation at IEEE/ACM DATE 2024.
October 2023: Dr. Ibrahim joined Georgia Tech (Center for the Co-Design of Cognitive Systems) to work as a Senior Research Staff, advised by Prof. Arijit Raychowdhury.
July 2022: Dr. Ibrahim will serve as a TPC member for DATE 2024.
October 2022: A poster of our work on hyperdimensional computing presented by Youbin Kim at IBM IEEE CAS/EDS AI Compute Symposium.
July 2022: Dr. Ibrahim will serve as a TPC member for DATE 2023.
March 2022: Dr. Ibrahim will serve as a TPC member for ICCAD 2022.
February 2022: Dr. Ibrahim will serve on the PC for ISVLSI 2022.
December 2021: A paper accepted at CLeaR 2022, a workshop to be held in conjunction with AAAI 2022.
November 2021: Dr. Ibrahim was invited to give a lecture on efficient hardware implementations of brain-inspired computing at Berkeley's Redwood Center for Theoretical Neuroscience. The lecture is part of Neuroscience 299.
September 2021: Dr. Ibrahim will serve as a session chair for ICCAD 2021.
August 2021: Our paper titled "Efficient Regulation of Synthetic Biocircuits Using Droplet-Aliquot Operations on MEDA Biochips" is accepted for publication at IEEE TCAD.
July 2021: Dr. Ibrahim is invited to serve on the PC for DATE 2022.
May 2021: Dr. Ibrahim joins UC Berkeley as a Postdoctoral Researcher. He will work on brain-inspired computing.
February 2021: Dr. Ibrahim is invited to serve as a TPC member for the 2021 ISVLSI. Here is the CFP.
January 2021: Dr. Ibrahim is invited to serve as a TPC member for the 8th ACM NanoCom 2021. Here is the CFP.
January 2021: Our journal paper, BioCyBig: A Cyberphysical System for Integrative Microfluidics-Driven Analysis of Genomic Association Studies, has been recommended by IEEE Transactions on Big Data to be referenced in IEEE Computer's "Spotlight on Transactions" column. Congratulations!
November 2020: Dr. Ibrahim attends ACM/IEEE MLCAD (virtually) to present his work on AdaPool.
October 2020: Dr. Ibrahim's paper, "AdaPool: Multi-Armed Bandits for Adaptive Virology Screening on Cyber-Physical Digital-Microfluidic Biochips", is accepted for publication in the ACM/IEEE Workshop on Machine Learning for CAD (MLCAD). Congratulations!
May 2020: Great news! Our research, "Molecular Barcoding as a Defense against Benchtop Biochemical Attacks on DNA Fingerprinting and Information Forensics", is showcased on Duke University Pratt School of Engineering's website! Check out this link. It also appeared on other pages such as phys.org.
May 2020: Good news! Our journal paper entitled "Molecular Barcoding as a Defense against Benchtop Biochemical Attacks on DNA Fingerprinting and Information Forensics" is accepted for publication in IEEE Transactions on Information Forensics & Security. Congratulations!
April 2020: Dr. Ibrahim will serve as a TPC member for DATE 2021.
March 2020: Dr. Ibrahim has finally completed Coursera specialization on Reinforcement Learning. Check out the Certificate.
January 2020: Dr. Ibrahim will serve as a TPC member for ISVLSI 2020.
November 2019: Mohamed is in Westminster, Colorado to attend ICCAD 2019 and present a paper on the "Internet of Microfluidic Things".
October 2019: Our journal paper entitled "Bio-chemical Assay Locking to Thwart Bio-IP Theft" is accepted for publication in the ACM TODAES! Congratulations!
October 2019: Dr. Ibrahim has finally completed Coursera specialization on Deep Learning. Check out the Certificate.
August 2019: Our paper entitled "Internet of Microfluidic Things: Perspectives on System Architecture and Design Challenges" is accepted at ICCAD 2019. The paper will be presented in a special session on microfluidics. Join us at ICCAD to learn more!
July 2019: Our paper entitled "Synterface: Efficient Chip-to-World Interfacing for Flow-Based Microfluidic Biochips Using Control-Pin Minimization" is accepted at CASES 2019. The paper will be published in the ACM Transactions on Embedded Computing Systems (TECS). Kudos to Aditya Sridhar who led this project while he was an undergraduate student at Duke!
June 2019: Mohamed to serve as a TPC member for DATE 2020.
May 2019: Good news! Mohamed received the 2019 Outstanding Dissertation Award from the department of Electrical and Computer Engineering at Duke University!.
March 2019: Mohamed is in Florence, Italy to present the "BioScan" paper at DATE 2019.
March 2019: Mohamed to serve as a TPC member for 27th IFIP/IEEE International Conference on Very Large Scale Integration (IFIP/IEEE VLSI-SoC 2019). The conference will be held in Peru in October 2019. Download the CFP.
March 2019: Our journal paper entitled "Analysis and Design of Tamper-Mitigating Microfluidic Routing Fabrics" is accepted for publication in IEEE TCAD. Congratulations!
Feb. 2019: Mohamed to serve as a TPC member for 6th ACM International Conference on Nanoscale Computing and Communication (ACM NanoCom 2019). Download the CFP.
Dec. 2018: Wonderful news! Mohamed was named the recipient of the 2018 Council of Graduate Schools/ProQuest Distinguished Dissertation Award in Mathematics, Physical Sciences, and Engineering! This is a prestigious award, and Mohamed was selected among other 68 applicants across the United States and Canada. Congratulations!.
Dec. 2018: Mohamed to serve as a TPC member for the IEEE Symposium on VLSI (ISVLSI 2019). Download the CFP.
Nov. 2018: Our article entitled "An Efficient Fault-Tolerant Valve-Based Microfluidic Routing Fabric for Droplet Barcoding in Single-Cell Analysis" is accepted for publication in IEEE TCAD!
Oct. 2018: Our article entitled "Synthesis of Tamper-Resistant Pin-Constrained Digital Microfluidic Biochips" is accepted for publication in IEEE TCAD. Congratulations!
Oct. 2018: Our paper entitled "BioScan: Parameter-Space Exploration of Synthetic Biocircuits Using MEDA Biochips" is accepted for publication in the Proceedings of IEEE/ACM DATE 2019. Congrats!
Sept. 2018: Our article entitled "Synthesis of Reconfigurable Flow-Based Biochips for Scalable Single-Cell Screening" is accepted for publication in IEEE TCAD. Congratulations!
Sept. 2018: Mohamed Ibrahim and Krish Chakrabarty signed a contract with CRC Press to publish a book entitled "Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms". The book will be based on Mohamed's PhD dissertation and will be in print by late 2019. Stay tuned!
Aug. 2018: Led by our NYU colleagues, a new book entitled "Secure and Trustworthy Cyberphysical Microfluidic Biochips" will be published in Springer Nature Switzerland by early 2019. Stay tuned!
July 2018: Mohamed to serve as a TPC member for IEEE VLSID 2019. CFP is here. Consider submitting your papers!
July 2018: Mohamed is one of two nominees of Duke University for the Council of Graduate Schools/ProQuest Distinguished Dissertation Award.
June 2018: Our keynote article entitled "Towards Secure and Trustworthy Cyberphysical Microfluidic Biochips" is accepted for publication in IEEE TCAD.
June 2018: Mohamed to serve as a TPC member for IEEE/ACM DATE 2019. CFP is here. Consider submitting to "A8: Industrial Experiences Brief ".
May 2018: Mohamed has successfully defended his Ph.D. dissertation!
May 2018: Our paper entitled "Synthesis of a Cyberphysical Hybrid Microfluidic Platform for Single-Cell Analysis" is accepted for publication in IEEE TCAD.
March 2018: Our paper on randomized checkpoints for cyber-physical digital microfluidic biochips is accepted for publication in IEEE Design & Test 2018.
Feb. 2018: Our paper on tamper-resistant pin-constrained digital microfluidic biochips is accepted for publication in IEEE/ACM DAC 2018.
Feb. 2018: Our paper on locking of biochemical assays is accepted for publication in IEEE ETS 2018.
Dec. 2017: Our keynote article on EDA for IoT eHealth is accepted for publication in IEEE Transactions on CAD.
Dec. 2017: Mr. Ibrahim is invited to attend IBM Watson Bootcamp in NCSU.
Dec. 2017: Our book chapter entitled "Digital Microfluidic Biochip Security" in "Security Opportunities by Nano Devices and Emerging Technologies" is in print.
Nov. 2017: Mr. Ibrahim finished his internship at Intel Santa Clara.
Nov. 2017: Mr. Ibrahim is in Irvine, CA to present a paper at IEEE/ACM ICCAD 2017.
Nov. 2017: Mr. Ibrahim passed his MSc exam (en route to PhD) in Electrical and Computer Engineering at Duke University!
Nov. 2017: Our paper entitled "Fault-Tolerant Valve-Based Microfluidic Routing Fabric for Droplet Barcoding in Single-Cell Analysis" is accepted for publication in IEEE/ACM DATE 2018.
Oct. 2017: Our paper entitled "Cyber-physical Digital Microfluidic Biochips: Bridging the Gap between Microfluidics and Microbiology" is accepted for publication in the Proceedings of IEEE, the flagship journal of the IEEE!
Sept. 2017: Our paper entitled "Exact Synthesis of Biomolecular Protocols for Multiple Sample Pathways on Digital Microfluidic Biochips" is accepted for publication in IEEE VLSID 2018.
August 2017: Our paper entitled "Security Trade-offs in Microfluidic Routing Fabrics" is accepted for publication in IEEE ICCD 2017.
July 2017: Our paper entitled "Secure Randomized Checkpointing for Digital Microfluidic Biochips" is accepted for publication in IEEE Transactions on CAD.
June 2017: Mr. Mohamed Ibrahim is in Austin, TX to present his PhD research at IEEE/ACM DAC PhD forum. Travel funded by ACM SIGDA.
June 2017: Our paper entitled "Sortex: Efficient Timing-Driven Synthesis of Reconfigurable Flow-Based Biochips for Scalable Single-Cell Screening" is accepted for publication in IEEE/ACM ICCAD 2017.
May 2017: Mr. Ibrahim started his 6-month internship at Intel Santa Clara.
April 2017: Mr. Ibrahim received ACM SIGDA Travel Award to present a poster in the Ph.D. Forum at IEEE/ACM DAC 2017.
April 2017: Mr. Ibrahim is invited to give a talk at TUM.
April 2017: Mr. Ibrahim is in Munich, Germany as a Visiting Scholar at the Technical University of Munich. Mohamed is hosted by Professor Ulf Schlichtmann.
March 2017: Mr. Ibrahim is in Lausanne, Switzerland to present a paper at the IEEE/ACM DATE 2017. Our paper has won the Best Paper award in the Application Track!
March 2017: Mr. Ibrahim is in Munich, Germany to attend Research Opportunities Week (ROW) at the Technical University of Munich (TUM). Mohamed's visit is fully funded by TUM.
March 2017: Mr. Ibrahim passed his preliminary exam towards his Ph.D.!
Dec. 2016: Our journal paper entitled "BioCyBig: A Cyberphysical System for Microfluidics-Driven Analysis of Integrative Genomic Association Studies" is accepted for publication in IEEE Transactions on Big Data.
Nov. 2016: Mr. Ibrahim and Prof. Chakrabarty are invited to write another paper in the proceedings of IEEE/ACM DATE 2017, and present it in a special session on EDA for microfluidics.
Oct. 2016: Mr. Ibrahim is in Arlington, VA to attend the NSF CPS PI Meeting and present a poster.
Oct. 2016: Mohamed is in Pittsburgh, PA to present a paper and poster at ESWeek 2016.
Sept. 2016: Mr. Ibrahim received ACM SIGBED Travel Award to present his paper at ESWeek 2016.
Sept. 2016: Mohamed gives a talk at Duke ECE Graduate Student Workshop.
Aug. 2016: Mr. Ibrahim finished his internship at Intel Austin.
Aug. 2016: Our paper entitled "Microfluidic Encryption of On-Chip Biochemical Assays" is accepted for publication in IEEE BioCAS 2016.
July 2016: Our manuscript entitled "Synthesis of Cyberphysical Digital-Microfluidic Biochips for Real-Time Quantitative Analysis" is accepted for publication in IEEE Transactions on CAD.
June 2016: Our paper entitled "Securing Digital Microfluidic Biochips by Randomizing Checkpoints" is accepted for publication in IEEE ITC 2016.
May 2016: Mr. Ibrahim started his internship at Intel Austin.
May 2016: Our paper entitled "A Real-Time Digital-Microfluidic Platform for Epigenetics" is accepted for publication in IEEE/ACM CASES 2016. To be presented in ESWeek 2016.
May 2016: Mr. Ibrahim is invited to give a talk at the University of Bremen.
May 2016: Mr. Ibrahim is in Bremen, Germany as a Visiting Scholar at the University of Bremen. Mohamed is hosted by Professor Rolf Drechsler.
April 2016: Our paper entitled "Supply-Chain Security of Digital-Microfluidic Biochips" is accepted for publication in IEEE Computer.
March 2016: Mr. Ibrahim is in Dresden, Germany to present a paper at IEEE/ACM DATE 2016.
About
Welcome! I am Mohamed Ibrahim, a Research Faculty Member at the Georgia Institute of Technology and an Incoming Assistant Professor at the University of Texas at Dallas starting in Fall 2025. Before joining Georgia Tech, I was a Postdoctoral Researcher at the University of California, Berkeley. My research focuses on efficient hardware-software co-design and optimization methodologies to advance embodied intelligence. This research combines brain-inspired computing, embedded cyber-physical integration, design automation, and VLSI AI hardware systems to develop cutting-edge algorithms and build innovative hardware architectures, aiming to create embodied AI systems that are inherently adaptable, reliable, and trustworthy.
I received my Ph.D. and M.Sc. degrees in 2018 and 2017, respectively, both in Electrical and Computer Engineering from Duke University. Following my PhD studies, I worked for three years in the semiconductor industry. I have also been on the technical program committees for multiple conferences, including ICCAD, DATE, ASAP, and ASP-DAC. Additionally, I serve as an expert reviewer for a large number of conferences and journals.
My research has been recognized with prestigious awards, including the Council of Graduate Schools/ProQuest Distinguished Dissertation Award in Mathematics, Physical Sciences, and Engineering, and an Outstanding Dissertation award from the department of Electrical and Computer Engineering at Duke University. I also received a Best Paper Award at the 2017 DATE Conference.
"I'm excited to share that I will be joining the University of Texas at Dallas as a tenure-track Assistant Professor in Electrical and Computer Engineering starting Fall 2025! If you’re interested in pursuing a PhD and joining my research group (The Embodied AI Circuits, Architectures, and Systems Group), feel free to reach out!"
Press
- 2025: Our Work on Integrated Acceleration of Cooperative Embodied AI [IAP]
- 2024: Our Work on Hardware-Software Co-Optimization of Neuro-Symbolic AI [Fortune]
- 2020: Our Work on Developing Genetic Barcodes to Ensure Authentic DNA Fingerprints [Duke's Pratt School of Engineering] [NYU's Tandon School of Engineering] [Phys.org] [WRAL] [NSF]
- 2018: Dr. Ibrahim Received 2018 Council of Graduate Schools(CGS)/ProQuest Distinguished Dissertation Award [Duke Graduate School]
Research Interests
- Computer Systems: AI Hardware; Embedded Systemds; Domain-Specific Accelerators; Hardware-Software Co-Design.
- Brain-Inspired Computing: Hyperdimensional Computing; Neuro-Symbolic AI; Foundation Models.
- VLSI and CAD: Digital Circuits Design; Design-for-Test; Energy Efficiency; Electronic Design Automation.
- Embodied Computing: Cyber-Physical Integration; Robotics; Smart Wearables.
Honors and Awards
- 2019: Recipient of ECE Outstanding Dissertation Award: Duke University.
- 2018: Recipient of the 2018 Council of Graduate Schools(CGS)/ProQuest Distinguished Dissertation Award: In the field of mathematics, physical sciences and engineering. Selected among other 68 applicants across the United States and Canada.
- 2017: DATE 2017 Best Paper Award: Lausanne, Switzerland.
- 2017: ACM-SIGDA 2017 DAC PhD Forum Travel Award: To present my PhD work in 2017 DAC PhD Forum.
- 2017: TUM Postdoc Mobility Award: Awarded to only 49 young scientists (including senior postdocs) from all over the world every year. Acceptance rate is 18%. Fully funded visit to TUM campus to explore research facilities and opportunities.
- 2016: ACM-SIGBD 2016 ESWeek Travel Award: To present our paper in 2016 IEEE/ACM CASES.
- 2015: Spotlight Paper: IEEE Transactions on Multi-scale Computing Systems (TMSCS).
- 2013: Duke Graduate School Fellowship: Awarded tuition and stipend for my Ph.D.
- 2010: Full Tuition Scholarship for Postgraduate Studies: Ain Shams University, Cairo, Egypt.
- 2010: Distinction Award, Graduation with Honors: Department of Computer and Systems Engineering, Ain Shams University, Cairo, Egypt.
Research Goal:
I envision a future where embodied human-centered computing systems, such as diagnostic devices, seamlessly integrate with human environments and biology, continuously evolving to meet individual needs and dynamically responding to changes in their surroundings. Driven by this vision, my goal is to enhance the capabilities of these systems by developing cognitive frameworks that are energy-efficient, robust, trustworthy, and explainable. Unlike existing solutions, my work focuses on creating sustainable sensory-motor cognitive capabilities that enable such systems to learn and adapt in real-time while optimizing energy use, ensuring long-term efficiency and reduced environmental impact. Furthermore, my research is inherently interdisciplinary, drawing inspiration from biological principles to design more adaptable and resilient systems. Central to this is the concept of algorithm-system-hardware co-design, where cognitive algorithms are developed in conjunction with customized system models and energy-efficient hardware architectures. This holistic design strategy fosters tight integration between computational processes and physical components, resulting in more scalable and robust systems than traditional siloed designs.
Current Research Projects
Coming soon...!
Past Research Projects
Hardwre-Software Codesign of Hybrid Microfluidic Biochips for Biomolecular Quantitative Analysis: System Modeling, Synthesis, and Optimization Methodologies

Considerable effort has been devoted in recent years to the design and implementation of microfluidic platforms for biomolecular quantitative analysis. However, today's platforms suffer from the drawback that they were optimized for sample limited analyses, thus they are inadequate for practical quantitative analysis and the processing of multiple samples through independent pathways. Design optimization techniques for microfluidics have been studied in recent years, but they overlook the myriad complexities of biomolecular protocols and are yet to make an impact in microbiology research. The realization of microfluidic platforms for real-life quantitative analysis requires a new optimization flow that is based on the realistic modeling of biomolecular protocols.
Motivated by the above needs, this project is focused on an optimized and trustworthy transfer of benchtop biomolecular analysis, particularly epigenetic studies, to programmable and cyber-physical microfluidic biochips. In collaboration with Duke Molecular Genetics and Microbiology, Mohamed has transferred gene-expression analysis and epigenetic protocols, e.g., chromatin immunoprecipitation, from bench-scale settings and has streamlined a generic optimization flow for various classes of biomolecular analysis protocols. Adopted optimization methods were based on cyber-physical system integration, real-time systems, CFD simulations, formal methods, modeling of stochastic processes, regression analysis, and more.
Selected Publications: [J4][J7][J10][J13]
Improving Trust in Emerging Microfluidic Biochips-based DNA Forensics

Microfluidics-driven biomolecular analysis can offer remarkable benefits, especially for mission-critical applications such as forensic DNA analysis. Several microfluidic commercial developers, including U.S.-based IntegenX, ANDE, and Lockheed Martin, have already started to roll out prototypes aiming to replace traditional benchtop procedures for DNA forensics, and it is anticipated that design automation and cyber-physical integration will play a significant role in advancing this technology. However, the pressure to drive down costs besides the proliferation of IoT-based connectedness will lead to cheap untrusted microfluidic devices and a multitude of unanticipated privacy violations if preventative measures are not taken. Trustworthy DNA forensic science are particularly relevant to defense applications and broader security needs.
Sensitive information in a microfluidic device can include data collected after processing of the fluids and personally identifying metadata. Irresponsible handling of patient data has led to the breakup of companies in the past, and current device makers would do well to learn from those mistakes. Other issues include trust in the sensor readings themselves; the rise and fall of Theranos, and the invalidation of two years worth of test results set a poor precedent for microuidics diagnostics. The nascent nature of microfluidics in biomolecular quantitative analysis presents an opportunity to incorporate security and trust in such critical applications before it becomes too late to rescue this rising industry from security threats.
Motivated by the above needs, this project is focused on creating the science of secure DNA forensics with the help of microfluidics technology. In collaboration with NYU Center for Cybersecurity (Professor Ramesh Karri's group) and Duke Molecular Genetics and Microbiology, Mohamed has worked on the assessment of the security implications of emerging forensic flows and has also provided appropriate countermeasures to secure such flows.
Selected Publications: [J2][J3][J19]
The Internet of Microfluidic Things: An Integrative Cyber-Physical System for Large-Scale Microfluidics-Driven Diagnostics

The integration of microfluidics and biosensor technology is transforming microbiology research by providing new capabilities for clinical diagnostics, cancer research, and pharmacology studies. This integration enables new approaches for biochemistry automation and cyber-physical adaptation. Similarly, recent years have witnessed the rapid growth of the Internet of Things (IoT) paradigm, where different types of real-world elements such as wearable sensors are connected and allowed to autonomously interact with each other. Combining the advances of both cyber-physical microfluidics and IoT domains can generate new opportunities for knowledge fusion by transforming distributed local microfluidic elements into a global network of coordinated microfluidic systems.
This research aims to streamline this transformation and it presents a research vision for enabling the Internet of Microfluidic Things (IoMT). To leverage advances in connected Microfluidic Things, the research introduces new perspectives on system architecture, and describe technical challenges related to design automation, temporal flexibility, security, and service assignment. This vision can play a critical role in advancing the responses of clinical healthcare to global pandemics such as COVID-19. It can also be used to support complex cancer research and pharmacology studies.
Selected Publications: [J5][J8][C19]
Hardware-Software Codesign for Real-Time Error Recovery in Cyber-Physical Digital Microfluidic Biochips

Digital microfluidics is a reconfigurable lab-on-chip technology that has achieved remarkable success in miniaturizing point-of-care (POC) quantitative-analysis testing. However, a major stumbling block in the monitoring and controlling of diseases via such POC systems is the lack of reliable diagnostic tests that can recover from unexpected errors. In addition, diagnostic tests, similar to all other quantitative-analysis procedures, are inherently stochastic systems that exhibit complex interactions among their constituent biochemical components. Such characteristics signify the need for real-time error-recovery methods that verify the correctness of on-chip fluidic interactions on-the-fly during bioassay execution.
To add resilience to digital-microfluidic control, Mohamed first introduced an efficient design method for digital microfluidic platforms to support error detection and recovery. The proposed design is based on cyber-physical system integration and it enables real-time monitoring of biochemical reactors (droplets) using capacitive sensors. Mohamed and his colleagues from Duke Microfluidics Lab designed and tested an all-hardware implementation of a cyber-physical microfluidic platform, thus enabling a portable POC setting that is resilient against faults.
Sample Publications: [J1][C1][C2]
Books
- Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms, Mohamed Ibrahim and Krishnendu Chakrabarty, CRC Press, 2020.
- Secure and Trustworthy Cyberphysical Microfluidic Biochips, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, Springer, 2020.
Book Chapters
- Digital Microfluidic Biochip Security, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri -- in Mark Tehranipoor, Domenic Forte, Garrett Rose, and Swarup Bhunia, ed., Security Opportunities by Nano Devices and Emerging Technologies, CRC Press, December 2017.
- Advances in Design Automation Techniques for Digital-Microfluidic Biochips, Mohamed Ibrahim, Zipeng Li, and Krishnendu Chakrabarty -- in Rolf Drechsler and Ulrich Kühne, ed., Formal Modeling and Verification of Cyber Physical Systems, pp. 190-223, Springer Fachmedien Wiesbaden, September 2015.
- Pin-Count and Wire Length Optimization for Electrowetting-on-Dielectric Chips: A Metaheuristics-Based Routing Algorithm, Mohamed Ibrahim, Cherif Salama, Mohamed Watheq El-Kharashi, and Ayman Wahba -- in Mourad Fakhfakh, Esteban Tlelo-Cuautle and Patrick Siarry, ed., Computational Intelligence in Digital and Network Designs and Applications, pp. 271-294, Springer International Publishing, 2015.
Journals
- Towards Efficient Neuro-Symbolic AI: From Workload Characterization to Hardware Architecture, Zishen Wan, Che-Kai Liu, Hanchen Yang, Ritik Raj, Chaojian Li, Haoran You, Yonggan Fu, Cheng Wan, Sixu Li, Youbin Kim, Ananda Samajdar, Yingyan (Celine) Lin, Mohamed Ibrahim, Jan M. Rabaey, Tushar Krishna, and Arijit Raychowdhury, IEEE Transactions on Circuits and Systems for Artificial Intelligence (TCASAI), 2024. [ Press: Fotune ]
- Efficient Regulation of Synthetic Biocircuits Using Droplet-Aliquot Operations on MEDA Biochips, Mohamed Ibrahim, Zhanwei Zhong, Bhargab B. Bhattacharya, and Krishnendu Chakrabarty, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2021.
- Molecular Barcoding as a Defense against Benchtop Biochemical Attacks on DNA Fingerprinting and Information Forensics, Mohamed Ibrahim, Tung-Che Liang, Kristin Scott, Ramesh Karri, and Krishnendu Chakrabarty, IEEE Transactions on Information Forensics & Security (TIFS), 2020. [ Press: Pratt School of Engineering - WRAL TechWire - Phys.org ]
- Bio-chemical Assay Locking to Thwart Bio-IP Theft, Sukanta Bhattacharjee, Jack Tang, Sudip Poddar, Mohamed Ibrahim, Ramesh Karri, and Krishnendu Chakrabarty, ACM Transactions on Design Automation of Electronic Systems (TODAES), 2019.
- Synterface: Efficient Chip-to-World Interfacing for Flow-Based Microfluidic Biochips Using Control-Pin Minimization, Aditya Sridhar, Mohamed Ibrahim, and Krishnendu Chakrabarty, ACM Transactions on Embedded Computing Systems (TECS), 2019.
- Analysis and Design of Tamper-Mitigating Microfluidic Routing Fabrics, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2019.
- An Efficient Fault-Tolerant Valve-Based Microfluidic Routing Fabric for Droplet Barcoding in Single-Cell Analysis, Yasamin Moradi, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ulf Schlichtmann, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2018.
- Synthesis of Tamper-Resistant Pin-Constrained Digital Microfluidic Biochips, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2018.
- Synthesis of Reconfigurable Flow-Based Biochips for Scalable Single-Cell Screening, Mohamed Ibrahim, Aditya Sridhar, Krishnendu Chakrabarty, and Ulf Schlichtmann, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2018. [ Technical Report ]
- Towards Secure and Trustworthy Cyberphysical Microfluidic Biochips, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2018. [ Keynote Paper ]
- Randomized Checkpoints: A Practical Defense for Cyberphysical Microfluidic Systems, Jack Tang, Mohamed Ibrahim, and Krishnendu Chakrabarty, IEEE Design & Test (D&T), 2018.
- Synthesis of a Cyberphysical Hybrid Microfluidic Platform for Single-Cell Analysis, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ulf Schlichtmann, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2018. [ Technical Report ]
- Randomized Checkpoints: A Practical Defense for Cyberphysical Microfluidic Systems, Jack Tang, Mohamed Ibrahim, and Krishnendu Chakrabarty, IEEE Design & Test (D&T), 2018.
- From EDA to IoT eHealth: Promises, Challenges, and Solutions, Farshad Firouzi, Bahar Farahani, Mohamed Ibrahim, and Krishnendu Chakrabarty, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2018. [ Keynote Paper ]
- Cyber-physical Digital-Microfluidic Biochips: Bridging the Gap between Microfluidics and Microbiology, Mohamed Ibrahim and Krishnendu Chakrabarty, Proceedings of the IEEE, 2018. [ 2016 Impact Factor = 9.237 ]
- Secure Randomized Checkpointing for Digital Microfluidic Biochips, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2017.
- BioCyBig: A Cyberphysical System for Microfluidics-Driven Analysis of Integrative Genomic Association Studies, Mohamed Ibrahim, Krishnendu Chakrabarty, and Jun Zeng, IEEE Transactions on Big Data (TBD), 2017.
- Synthesis of Cyberphysical Digital-Microfluidic Biochips for Real-Time Quantitative Analysis, Mohamed Ibrahim, Krishnendu Chakrabarty, and Kristin Scott, IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), 2016.
- Supply-Chain Security of Digital-Microfluidic Biochips, Sk Subidh Ali, Mohamed Ibrahim, Jeyavijayan Rajendran, Ozgur Sinanoglu, and Krishnendu Chakrabarty, IEEE Computer, 2016. [ "Cover Feature" in the August 2016 issue of IEEE Computer ]
- Security Assessment of Cyberphysical Digital-Microfluidic Biochips, Sk Subidh Ali, Mohamed Ibrahim, Ozgur Sinanoglu, Krishnendu Chakrabarty, and Ramesh Karri, IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB), 2015.
- Efficient Error Recovery in Cyberphysical Digital-Microfluidic Biochips, Mohamed Ibrahim and Krishnendu Chakrabarty, IEEE Transactions on Multiscale Computing Systems (TMSCS), 2015.
Conference Papers
- HPU: a 168pJ/op Multi-Purpose and Multi-Dimension Binary Hyper-Dimensional Processing Unit for Energy-Efficient Machine Learning, Youbin Kim, Mohamed Ibrahim, and Jan Rabaey, IEEE European Solid-State Electronics Research Conference (ESSERC), 2025.
- ReCA: Integrated Acceleration for Real-Time and Efficient Cooperative Embodied Autonomous Agents, Zishen Wan, Yuhang Du, Mohamed Ibrahim, Jiayi Qian, Jason Jabbour, Yang (Katie) Zhao, Vijay Janapa Reddi, Tushar Krishna, and Arijit Raychowdhury, Proceedings of ACM International Conference on Architectural Support for Programming Languages and Operating Systems (ASPLOS), 2025.
- Thinking and Moving: An Efficient Computing Approach for Integrated Task and Motion Planning in Cooperative Embodied AI Systems, Zishen Wan, Yuhang Du, Mohamed Ibrahim, Yang (Katie) Zhao, Tushar Krishna, Arijit Raychowdhury, Proceedings of the IEEE/ACM International Conference on Computer-Aided Design (ICCAD), 2024.
- Neuro-Symbolic Architecture Meets Large Language Models: A Memory-Centric Perspective, Mohamed Ibrahim, Zishen Wan, Haitong Li, Priyadarshini Panda, Tushar Krishna, Pentti Kanerva, Yiran Chen, and Arijit Raychowdhury, Proceedings of IEEE/ACM International Conference on Hardware/Software Codesign and System Synthesis (CODES+ISSS), 2024.
- H3DFact: Heterogeneous 3D Integrated CIM for Factorization with Holographic Perceptual Representations, Zishen Wan, Che-Kai Liu, Mohamed Ibrahim, Hanchen Yang, Samuel Spetalnick, Tushar Krishna, and Arijit Raychowdhury, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2024.
- Efficient Design of a Hyperdimensional Processing Unit for Multi-Layer Cognition, Mohamed Ibrahim, Youbin Kim, and Jan M. Rabaey, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2024.
- A Brain-Inspired Hierarchical Reasoning Framework for Cognition-Augmented Prosthetic Grasping, Laura I. Galindez Olascoaga, Alisha Menon, Mohamed Ibrahim, and Jan M. Rabaey, International Workshop on Combining Learning and Reasoning: Programming Languages, Formalisms, and Representations (CLeaR), 2022.
- AdaPool: Multi-Armed Bandits for Adaptive Virology Screening on Cyber-Physical Digital-Microfluidic Biochips, Mohamed Ibrahim, Proceedings of the ACM/IEEE Workshop on Machine Learning for CAD (MLCAD), 2020.
- Internet of Microfluidic Things: Perspectives on System Architecture and Design Challenges, Mohamed Ibrahim, Maria Gorlatova, and Krishnendu Chakrabarty, Proceedings of the IEEE/ACM International Conference on Computer-Aided Design (ICCAD), 2019.
- BioScan: Parameter-Space Exploration of Synthetic Biocircuits Using MEDA Biochips, Mohamed Ibrahim, Bhargab Bhattacharya, and Krishnendu Chakrabarty, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2019.
- Tamper-Resistant Pin-Constrained Digital Microfluidic Biochips, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE/ACM Design Automation Conference (DAC), 2018.
- Locking of Biochemical Assays for Digital Microfluidic Biochips, Sukanta Bhattacharjee, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE European Test Symposium (ETS), 2018.
- Fault-Tolerant Valve-Based Microfluidic Routing Fabric for Droplet Barcoding in Single-Cell Analysis, Yasamin Moradi, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ulf Schlichtmann, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2018.
- Exact Synthesis of Biomolecular Protocols for Multiple Sample Pathways on Digital Microfluidic Biochips, Oliver Keszocze, Mohamed Ibrahim, Robert Wille, Krishnendu Chakrabarty, and Rolf Drechsler, Proceedings of the IEEE International Conference on VLSI Design (VLSID), pp. 121-126, 2018.
- Security Trade-offs in Microfluidic Routing Fabrics, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE International Conference on Computer Design (ICCD), 2017.
- Security Implications of Cyberphysical Flow-Based Microfluidic Biochips, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE Asian Test Symposium (ATS), 2017.
- Sortex: Efficient Timing-Driven Synthesis of Reconfigurable Flow-Based Biochips for Scalable Single-Cell Screening, Mohamed Ibrahim, Aditya Sridhar, Krishnendu Chakrabarty, and Ulf Schlichtmann, Proceedings of the IEEE/ACM International Conference on Computer-Aided Design (ICCAD), 2017.
- Digital-Microfluidic Biochips for Quantitative Analysis: Bridging the Gap between Microfluidics and Microbiology, Mohamed Ibrahim and Krishnendu Chakrabarty, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2017.
- CoSyn: Efficient Single-Cell Analysis Using a Hybrid Microfluidic Platform, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ulf Schlichtmann, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2017. [ Received Best Paper Award! ][ Extended Technical Report ]
- Cyberphysical Adaptation in Digital-Microfluidic Biochips, Mohamed Ibrahim and Krishnendu Chakrabarty, Proceedings of the IEEE Biomedical Circuits & Systems Conference (BioCAS), 2016.
- Microfluidic Encryption of On-Chip Biochemical Assays, Sk Subidh Ali, Mohamed Ibrahim, Ozgur Sinanoglu, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE Biomedical Circuits & Systems Conference (BioCAS), 2016.
- Securing Digital-Microfluidic Biochips by Randomizing Checkpoints, Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE International Test Conference (ITC), 2016.
- A Real-Time Digital-Microfluidic Platform for Epigenetics, Mohamed Ibrahim, Craig Boswell, Krishnendu Chakrabarty, Kristin Scott, and Miroslav Pajic, Proceedings of the IEEE/ACM International Conference on Compilers, Architectures and Synthesis For Embedded Systems (CASES), 2016.
- Integrated and Real-Time Quantitative Analysis Using Cyberphysical Digital-Microfluidic Biochips, Mohamed Ibrahim, Krishnendu Chakrabarty, and Kristin Scott, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2016.
- Security Implications of Cyber-Physical Digital-Microfluidic Biochips, Sk Subidh Ali, Mohamed Ibrahim, Ozgur Sinanoglu, Krishnendu Chakrabarty, and Ramesh Karri, Proceedings of the IEEE International Conference on Computer Design (ICCD), 2015.
- Experimental Demonstration of Error Recovery in an Integrated Cyberphysical Digital-Microfluidic Platform, Kai Hu, Mohamed Ibrahim, Liji Chen, Zipeng Li, Krishnendu Chakrabarty, and Richard Fair, Proceedings of the IEEE Biomedical Circuits & Systems Conference (BioCAS), 2015.
- Error Recovery in Digital Microfluidics for Personalized Medicine, Mohamed Ibrahim and Krishnendu Chakrabarty, Proceedings of the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), 2015.
Posters & Talks
- Biologically Inspired Neuro-Symbolic Computing for Human-Centered AI, Talk at UT Dallas, Dallas, Texas, January 2025.
- Efficient Design of a Hyperdimensional Processing Unit for Multi-Layer Cognition, Talk and Poster at the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), Valencia, Spain, March 2024.
- The Hyperdimensional Processing Unit, Poster at IBM IEEE CAS/EDS AI Compute Symposium, Yorktown Heights, New York, USA, October 2022. [ Presented by Youbin Kim ]
- AdaPool: Multi-Armed Bandits for Adaptive Virology Screening on Cyber-Physical Digital-Microfluidic Biochips, Talk at the ACM/IEEE Workshop on Machine Learning for CAD (MLCAD), Virtual, November 2020.
- Internet of Microfluidic Things: Perspectives on System Architecture and Design Challenges, Talk at the IEEE/ACM International Conference on Computer-Aided Design (ICCAD), Colorado, USA, November 2019.
- BioScan: Parameter-Space Exploration of Synthetic Biocircuits Using MEDA Biochips, Talk at the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), Florence, Italy, March 2019.
- Sortex: Efficient Timing-Driven Synthesis of Reconfigurable Flow-Based Biochips for Scalable Single-Cell Screening, Talk at the IEEE/ACM International Conference on Computer-Aided Design (ICCAD), Irvine, California, USA, November 2017.
- Design and Optimization of Microfluidic Platforms for Scalable Biomolecular Quantitative Analysis, Poster at the SIGDA PhD Forum, IEEE/ACM Design Automation Conference (DAC), Austin, Texas, USA, June 2017.
- Hacking Digital Microfluidic High-Level Synthesis, Poster at Hack@DAC contest, IEEE/ACM Design Automation Conference (DAC), Austin, Texas, USA, June 2017. [Presented by Jack Tang ]
- CoSyn: Efficient Single-Cell Analysis Using a Hybrid Microfluidic Platform, Invited Talk at the Technical University of Munich, Munich, Germany, April 2017.
- CoSyn: Efficient Single-Cell Analysis Using a Hybrid Microfluidic Platform, Talk at the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), Lausanne, Switzerland, March 2017.
- Cyberphysical Integration for Digital Microfluidic Biochips, Poster at the NSF CPS PI Meeting, Arlington, Virginia, USA, November 2016.
- A Real-Time Digital-Microfluidic Platform for Epigenetics, Talk and poster at the Embedded Systems Week (ESWeek), Pittsburgh, Pennsylvania, USA, October 2016.
- A Real-Time Digital-Microfluidic Platform for Epigenetics, Talk at Duke ECE Graduate Student Workshop, Durham, North Carolina, USA, September 2016.
- Design and Automated Control of Cyberphysical Digital-Microfluidic Biochips: From Error Recovery Towards Quantitative Analysis, Invited Talk at the University of Bremen, Bremen, Germany, May 2016.
- Integrated and Real-Time Quantitative Analysis Using Cyberphysical Digital-Microfluidic Biochips, Talk at the IEEE/ACM Design, Automation and Test in Europe Conference (DATE), Dresden, Germany, March 2016.
- Integrated and Real-Time Quantitative Analysis Using Cyberphysical Digital-Microfluidic Biochips, Poster at Duke ECE Graduate Student Workshop, Durham, North Carolina, USA, September 2015.
- Experimental Demonstration of Error Recovery in an Integrated Cyberphysical Digital-Microfluidic Platform, Talk at IEEE Biomedical Circuits & Systems Conference (BioCAS), Atlanta, Georgia, USA, October 2015.
- Cyberphysical Integration for Digital Microfluidic Biochips, Poster at the NSF CPS PI Meeting, Arlington, Virginia, USA, November 2014.
Teaching
UC Berkeley:
- 2021: Computing with High-Dimensional Vectors (Neuroscience 299): Guest Lecturer
Duke University:
- 2018: VLSI System Testing (ECE-538): Graduate Teaching Assistant
- 2016: CMOS VLSI Design Methodologies (ECE-539): Guest Lecturer
- 2015: Programming, Data Structure, and Algorithms in C++ (ECE-551): Graduate Teaching Assistant
- 2014: Computer Architecture (ECE-250): Graduate Teaching Assistant
Ain Shams University:
- 2011-2013: Computer Organization I (CSE-211): Teaching Assistant
- 2012-2013: Computer Organization II (CSE-311): Teaching Assistant
- 2011-2012: System Dynamics and Control Components (CSE-271): Teaching Assistant
- 2011-2012: System Modeling and Simulation (CSE-467): Teaching Assistant
Proposal Writing
During my Ph.D. studies, I worked with my advisor, Professor Chakrabarty, on four grant proposals. I made major contributions to the following funded grants:
- 2017: National Science Foundation "CCF-1702596": Microbiology on a Programmable Biochip: An Integrated Hardware/Software Digital Microfluidics Platform.
- 2017: U.S. Department of Defense, Army Research Office (ARO) "W911NF-17-1-0320": Improving Trust in Emerging Digital Microfluidic Biochips-based DNA Forensics.
Academic Services
Technical Program Committee Member:
- IEEE/ACM Design, Automation and Test in Europe Conference (DATE): 2019 - Present.
- IEEE/ACM International Conference on Computer-Aided Design (ICCAD): 2021 - Present.
- IEEE International Conference on Application-specific Systems, Architectures and Processors (ASAP): 2025 - Present.
- IEEE/ACM Asia and South Pacific Design Automation Conference (ASP-DAC): 2025 - Present.
- IEEE Computer Society Annual Symposium on VLSI (ISVLSI): 2019 - 2022.
- IEEE International Conference on VLSI Design (VLSID): 2019, 2026.
- IFIP/IEEE International Conference on Very Large Scale Integration (VLSI-SoC): 2019.
Journal Reviewer:
- IEEE Transactions on Circuits and Systems for Artificial Intelligence (TCASAI)
- IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD)
- IEEE Transactions on Very Large Scale Integration Systems (TVLSI)
- IEEE Transactions on Biomedical Circuits and Systems (TBioCAS)
- ACM Transactions on Design Automation of Electronic Systems (ACM TODAES)
- ACM Journal on Emerging Technologies in Computing Systems (ACM JETC)
- Integration, the VLSI Journal (Elsevier)
- Microelectronics Journal
Conference Reviewer:
- IEEE/ACM Design, Automation and Test in Europe Conference (DATE)
- IEEE/ACM Design Automation Conference (DAC)
- IEEE/ACM International Conference on Computer-Aided Design (ICCAD)
- IEEE International Symposium on Circuits and Systems (ISCAS)
- IEEE European Test Symposium (ETS)
- ACM International Conference on Nanoscale Computing and Communication (NanoCom)
- IEEE International Conference on Artificial Intelligence Circuits and Systems (AICAS)
Mentorship
Georgia Tech:
- Zishen Wan: Ph.D. student (2023 - 2025).
UC Berkeley:
- E. Lin, J. Qiao, L. Zhang: MEng Students -- through Berkeley's Fung Institute Leadership Program (2023 - 2024).
- S. Desai, Y. He, A. Pan, N. Santoso, W. Sun, C. Symes, and Y. Wang: MEng Students -- through Berkeley's Fung Institute Leadership Program (2022 - 2023).
Duke University:
- Emily Zhao: Undergraduate CS/ECE Student -- through Pratt Alumni Mentorship Program (2024 - 2025).
- Aditya Sridhar: Undergraduate CS Student (2016 - 2018).
- Craig Boswell: Pratt Undergraduate Fellow (2015 - 2016).
Technical University of Munich:
- Yasamin Moradi: Ph.D. student (2016 - 2017).
Industry
- 2019 - 2021: SoC Design Engineer (Full Time), Intel Santa Clara, CA, USA.
- 2017: DFT Engineer (Internship), Intel Santa Clara, CA, USA.
- 2015, 2016: SoC DFX Design Engineer (Internship), Intel Austin, TX, USA.
- 2011 - 2013: VLSI Design and Verification Engineer (Part Time), Newport Media Inc., Cairo, Egypt.
- 2010 - 2011: VLSI Design Engineer (Full Time), Mentor Graphics, Cairo, Egypt.
- 2009: Embedded Systems Engineer (Internship), Mentor Graphics, Cairo, Egypt.