SAR study indicates that the main structural feature regarding phenolic compounds forced to possess good antiradical and antioxidant activities may be the presence of an extra hydroxyl or a good amino group within o- or p-position for their strong electron giving effect in these positions along with the formation of synthetic cannabinoids like products on two hydrogen-atom transport process; otherwise, the presence of numerous alkoxy (inside o or p-position) and also /or alkyl groups (in i, m or p-position) needs to be present to stabilize the resulted phenoxyl significant and reach good activity.
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