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2022 | Medical science

Gut metagenome associations with extensive digital health data in a volunteer-based Estonian microbiome cohort.

Aasmets, Oliver; Krigul, Kertu L; Lüll, Kreete; Metspalu, Andres; Org, Elin (2022). Nature Communications, 13 (1), 1−11. DOI: 10.1038/s41467-022-28464-9.

2022 | Biology

Global patterns in endemicity and vulnerability of soil fungi.

Tedersoo, Leho; Mikryukov, Vladimir; Zizka, Alexander; Bahram, Mohammad; Hagh-Doust, Niloufar; Anslan, Sten; Prylutskyi, Oleh; Delgado-Baquerizo, Manuel; Maestre, Fernando T; … Abarenkov, Kessy (2022). Global Change Biology, 28 (22), 6696−6710. DOI: 10.1111/gcb.16398.

2022 | Medical science

SARS-CoV-2 dual infection with Delta and Omicron variants in an immunocompetent host: a case report.

Abroi, Aare; Gerst Talas, Ulvi; Pauskar, Merit; Shablinskaja, Arina; Reisberg, Tuuli; Niglas, Heiki; Pall, Taavi; Nelis, Mari; Tagen, Ingrid; Soodla, Pilleriin; Lutsar, Irja; Huik, Kristi (2022). International Journal of Infectious Diseases, 124, 41−44. DOI: 10.1016/j.ijid.2022.08.027.

2022 | Medical science

Genetic variants that edit risk of immune diseases.

Alasoo, Kaur (2022). Nature, 608, 479−480. DOI: 10.1038/d41586-022-01641-y.

2022 | Chemistry

CO2 reduction to formate on an affordable bismuth metal-organic framework based catalyst.

Ávila-Bolívar, Beatriz; Cepitis, Ritums; Alam, Mahboob; Assafrei, Jürgen-Martin; Ping, Kefeng; Aruväli, Jaan; Kikas, Arvo; Kisand, Vambola; Vlassov, Sergei; Käärik, Maike; Leis, Jaan; Ivaništšev, Vladislav; Starkov, Pavel; Montiel, Vicente; Solla-Gullón, José; Kongi, Nadezda (2022). Journal of CO2 Utilization, 59, 101937. DOI: 10.1016/j.jcou.2022.101937.

2022 | Biology

Structure and function of the soil microbiome underlying N2O emissions from global wetlands.

Bahram, Mohammad; Espenberg, Mikk; Pärn, Jaan; Lehtovirta-Morley, Laura; Anslan, Sten; Kasak, Kuno; Kõljalg, Urmas; Liira, Jaan; Maddison, Martin; Moora, Mari; Niinemets, Ülo; Öpik, Maarja; Pärtel, Meelis; Soosaar, Kaido; Zobel, Martin; Hildebrand, Falk; Tedersoo, Leho; Mander, Ülo (2022). Nature Communications, 13, 1430. DOI: 10.1038/s41467-022-29161-3.

2022 | Medical science

Immune disease variants modulate gene expression in regulatory CD4+ T cells.

Bossini-Castillo, Lara; Glinos, Dafni A.; Kunowska, Natalia; Golda, Gosia; Lamikanra, Abigail A.; Spitzer, Michaela; Soskic, Blagoje; Cano-Gamez, Eddie; Smyth, Deborah J.; Cattermole, Claire; Alasoo, Kaur; Mann, Alice; Kundu, Kousik; Lorenc, Anna; Soranzo, Nicole; Dunham, Ian; Roberts, David J.; Trynka, Gosia (2022). Cell Genomics, 2 (4), 100117. DOI: 10.1016/j.xgen.2022.100117.

2022 | NLP

Cross-lingual Similarity of Multilingual Representations Revisited.

Del, Maksym; Fishel, Mark (2022). In: Proceedings of the 2nd Conference of the Asia-Pacific Chapter of the Association for Computational Linguistics and the 12th International Joint Conference on Natural Language Processing (Volume 1: Long Papers), pages 185−195. Association for Computational Linguistics. DOI: https://arxiv.org/abs/2212.01924.

2022 | NLP

Similarity of Sentence Representations in Multilingual LMs: Resolving Conflicting Literature and a Case Study of Baltic Languages.

Del, Maksym; Fishel, Mark; (2022). Baltic Journal of Modern Computing, 10 (3), 337−347. DOI: 10.22364/bjmc.2022.10.3.07.

2022 | NLP

Language resources and tools for Livonian.

Ernštreits, Valts; Fišel, Mark; Rikters, Matīss; Tomingas, Marili; Tuisk, Tuuli (2022). Journal of Estonian and Finno-Ugric Linguistics, 13 (1), 13−36. DOI: 10.12697/jeful.2022.13.1.01.

2022 | Medical science

Heterozygote selection against ID alleles may shape the landscape of autosomal-recessive pathogenic variants in European populations.

Fridman, Hila; Yntema, Helger G.; Magi, Reedik; Andreson, Reidar; Metspalu, Andres; Mezzavila, Massimo; Tyler-Smith, Chris; Xue, Yali; Carmi, Shai; Levy-Lahad, Ephrat; Gilissen, Christian; Brunner, Han G. (2022). European Journal of Human Genetics, 30 (SUPPL 1, 1), 537−538.

2022 | Medical science

BIRC6 modifies risk of invasive bacterial infection in Kenyan children.

Gilchrist, James; Kariuki, Silvia N; Watson, James A; Band, Gavin; Uyoga, Sophie; Ndila, Carolyne M; Mturi, Neema; Mwarumba, Salim; Mohammed, Shebe; Mosobo, Moses; Alasoo, Kaur; Rockett, Kirk A; Mentzer, Alexander J; Kwiatkowski, Dominic P; Hill, Adrian VS; Maitland, Kathryn; Scott, J Anthony G; Williams, Thomas N (2022). eLife, 11, e77461. DOI: 10.7554/eLife.77461.

2022 | Medical science

An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim.

Guellil, Meriam; Keller, Marcel; Dittmar, Jenna M.; Inskip, Sarah A.; Cessford, Craig; Solnik, Anu; Kivisild, Toomas; Metspalu, Mait; Robb, John E.; Scheib, Christiana L. (2022). Genome Biology, 23 (1). DOI: 10.1186/s13059-021-02580-z.

2022 | Biology

Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia.

Guellil, Meriam; van Dorp, Lucy; Inskip, Sarah A.; Dittmar, Jenna M.; Saag, Lehti; Tambets, Kristiina; Hui, Ruoyun; Rose, Alice; D’Atanasio, Eugenia; Kriiska, Aivar; Varul, Liivi; Koekkelkoren, A. M. H. C.; Goldina, Rimma D.; Cessford, Craig; Solnik, Anu; Metspalu, Mait; Krause, Johannes; Herbig, Alexander; Robb, John E.; Houldcroft, Charlotte J. Scheib, Christiana L. (2022). Science Advances, 8 (30), eabo4435. DOI: 10.1126/sciadv.abo4435.

2022 | Medical science

Precise, Genotype-First Breast Cancer Prevention: Experience With Transferring Monogenic Findings From a Population Biobank to the Clinical Setting.

Jurgens, Hannes; Roht, Laura; Leitsalu, Liis; Noukas, Margit; Palover, Marili; Nikopensius, Tiit; Reigo, Anu; Kals, Mart; Kallak, Kersti; Kuetner, Riina; Budrikas, Kai; Kuusk, Saskia; Valvere, Vahur; Laidre, Piret; Toome, Kadri; Rekker, Kadri; Tooming, Mikk; Kahre, Tiina; Kruuv-Kao, Krista; ounap, Katrin … Tonisson, Neeme (2022). Frontiers in Genetics, 13, 881100. DOI: 10.3389/fgene.2022.881100.

2022 | Medical science

Editorial: Can population health be personalized? Estonia and Finland as examples.

Kaariainen, Helena; Metspalu, Andres; Perola, Markus (2022). Frontiers in Genetics, 13, 1051085. DOI: 10.3389/fgene.2022.1051085.

2022 | Biology

Episodes of diversification and isolation in Island Southeast Asian and Near Oceanian male lineages.

Karmin, Monika; Flores, Rodrigo; Saag, Lauri; Hudjashov, Georgi; Brucato, Nicolas; Crenna- Darusallam Chelzie, Larena Maximilian, Endicott Phillip, Jakobsson Mattias, Lansing Stephen, Sudoyo Herawati, Leavesley Matthew, Metspalu Mait, Ricaut François-Xavier, Cox Murray (2022). Molecular Biology and Evolution, 39 (3), msac045. DOI: 10.1093/molbev/msac045.

2022 | NLP

Findings of the 2022 Conference on Machine Translation (WMT22).

Kocmi, Tom; Bawden, Rachel; Bojar, Ondrej; Dvorkovich, Anton; Federmann, Christian; Fishel, Mark; Gowda, Thamme; Graham, Yvette; Grundkiewicz, Roman; Haddow, Barry; Knowles, Rebecca; Koehn, Philipp; Monz, Christof; Morishita, Makoto; Nagata, Masaaki; Nakazawa, Toshiaki; Novak, Michal; Popel, Martin; Popovic, Maja (2022). In: Proceedings of the Seventh Conference on Machine Translation (WMT), pages 1−45. Association for Computational Linguistics.

2022 | NLP

Estonian Language Understanding: a Case Study on the COPA Task.

Kuulmets, Hele-Andra; Tättar, Andre; Fišel, Mark (2022). Baltic Journal of Modern Computing, 10, 470−480. DOI: 10.22364/bjmc.2022.10.3.19.

2022 | Medical science

Trajectories: a framework for detecting temporal clinical event sequences from health data standardized to the Observational Medical Outcomes Partnership (OMOP) Common Data Model.

Künnapuu, Kadri; Ioannou, Solomon; Ligi, Kadri; Kolde, Raivo; Laur, Sven; Vilo, Jaak; Rijnbeek, Peter R; Reisberg, Sulev (2022). JAMIA Open, 5 (1), 1−11. DOI: 10.1093/jamiaopen/ooac021.

2022 | Chemistry

Quantifying Acidity in Heterogeneous Systems: Biphasic pKa Values.

Leesment, Andre; Selberg, Sigrid; Tammiste, Merili; Vu, Anh H; Nguyen, Thuong H; Taylor-King, Luke; Leito, Ivo (2022). Analytical Chemistry, 94 (9), 4059−4064. DOI: 10.1021/acs.analchem.1c05510.

2022 | Medical science

Lessons learned during the process of reporting individual genomic results to participants of a population-based biobank.

Leitsalu, Liis; Reigo, Anu; Palover, Marili; Nikopensius, Tiit; Lall, Kristi; Krebs, Kristi; Reisberg, Sulev; Magi, Reedik; Kals, Mart; Alavere, Helene; Noukas, Margit; Kolk, Anneli; Normet, Ivi; Tammesoo, Mari-Liis; Kaarik, Ene; Puusepp, Mairo; Metsalu, Kristjan; Allik, Annely; Milani, Lili; Fischer, Krista … Metspalu, Andres (2022). European Journal of Human Genetics, 31 (9). DOI: 10.1038/s41431-022-01196-6.

2022 | Medical science

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.

Mahajan, Anubha; Spracklen, Cassandra N; Zhang, Weihua; Ng, Maggie C Y; Petty, Lauren E; Kitajima, Hidetoshi; Yu, Grace Z; RĆ¼eger, Sina; Speidel, Leo; Kim, Young Jin; Horikoshi, Momoko; Mercader, Josep M; Taliun, Daniel; Moon, Sanghoon; Kwak, Soo-Heon; Robertson, Neil R; Rayner, Nigel W; Loh, Marie; Kim, Bong-Jo; Chiou, Joshua … Morris, Andrew P. (2022). Nature Genetics, 54 (5), 560−572. DOI: 10.1038/s41588-022-01058-3.

2022 | Biology

Ancestral genomic contributions to complex traits in contemporary Europeans.

Marnetto, Davide; Pankratov, Vasili; Mondal, Mayukh; Montinaro, Francesco; Pärna, Katri; Vallini, Leonardo; Molinaro, Ludovica; Saag, Lehti; Loog, Liisa; Montagnese, Sara; Costa, Rodolfo; Metspalu, Mait; Eriksson, Anders; Pagani, Luca (2022). Current Biology, 32 (6). DOI: 10.1016/j.cub.2022.01.046.

2022 | Biology

Unraveling a fine-scale high genetic heterogeneity and recent continental connections of an Arabian Peninsula population.

Eaaswarkhanth, Muthukrishnan; Pathak, Ajai K.; Ongaro, Linda; Montinaro, Francesco; Hebbar, Prashantha; Alsmadi, Osama; Metspalu, Mait; Al-Mulla, Fahd; Thanaraj, Thangavel Alphonse (2022). European Journal of Human Genetics, 30. DOI: 10.1038/s41431-021-00861-6.

2022 | Biology

Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with global and local ancestries.

Natri, Heini M.; Hudjashov, Georgi; Jacobs, Guy; Kusuma, Pradiptajati; Saag, Lauri; Darusallam, Chelzie Crenna; Metspalu, Mait; Sudoyo, Herawati; Cox, Murray P.; Romero, Irene Gallego; Banovich, Nicholas E. (2022). The American Journal of Human Genetics, 109 (1), 50−65. DOI: 10.1016/j.ajhg.2021.11.017.

2022 | Medical science

Genetic and modifiable risk factors combine multiplicatively in common disease.

Pang, Shichao; Yengo, Loic; Nelson, Christopher P.; Bourier, Felix; Zeng, Lingyao; Li, Ling; Kessler, Thorsten; Erdmann, Jeanette; Magi, Reedik; Lall, Kristi; Metspalu, Andres; Mueller-Myhsok, Bertram; Samani, Nilesh J.; Visscher, Peter M.; Schunkert, Heribert (2022). Clinical Research in Cardiology, 112 (2). DOI: 10.1007/s00392-022-02081-4.

2022 | Medical science

A first update on mapping the human genetic architecture of COVID-19.

Pathak, Gita A; Polimanti, Renato; Karjalainen, Juha; Daly, Mark; Ganna, Andrea; Daly, Mark J; Stevens, Christine; Kanai, Masahiro; Liao, Rachel G; Trankiem, Amy; Balaconis, Mary K; Nguyen, Huy; Solomonson, Matthew; Veerapen, Kumar; Ripatti, Samuli; Nkambul, Lindo; Bryant, Sam; Sankaran, Vijay G; Neale, Benjamin M; Karczewski, Konrad J; … Biesecker, Les (2022). Nature, 608 (7921), E1−E10. DOI: 10.1038/s41586-022-04826-7.

2022 | Medical science

Spectrum and frequency of CHEK2 variants in breast cancer affected and general population in the Baltic states region, initial results and literature review.

Pavlovica, Kristine; Irmejs, Arvids; Noukas, Margit; Palover, Marili; Kals, Mart; Tonisson, Neeme; Metspalu, Andres; Gronwald, Jacek; Lubinski, Jan; Murmane, Daiga; Kalnina, Agnese; Loza, Peteris; Maksimenko, Jelena; Trofimovics, Genadijs; Subatniece, Signe; Daneberga, Zanda; Miklasevics, Edvins; Gardovskis, Janis (2022). European Journal of Medical Genetics, 65 (5), 104477. DOI: 10.1016/j.ejmg.2022.104477.

2022 | Chemistry

Measurements and Utilization of Consistent Gibbs Energies of Transfer of Single Ions: Towards a Unified Redox Potential Scale for All Solvents.

Radtke, Valentin; Gebel, Niklas; Priester, Denis; Ermantraut, Andreas; Baeuerle, Monika; Himmel, Daniel; Stroh, Regina; Koslowski, Thorsten; Leito, Ivo; Krossing, Ingo (2022). Chemistry - A European Journal, e202200509. DOI: 10.1002/chem.202200509.

2022 | Chemistry

Novel Lipophilic Fluorophores with Highly Acidity-Dependent Two-Photon Response.

Rammo, Matt; Trummal, Aleksander; Uudsemaa, Merle; Pahapill, Juri; Petritsenko, Katrin; Sildoja, Meelis-Mait; Stark, Charles W.; Selberg, Sigrid; Leito, Ivo; Palmi, Kirsti; Adamson, Jasper; Rebane, Aleksander (2022). Chemistry - A European Journal, 28 (8). DOI: 10.1002/chem.202103707.

2022 | Physics

Chlorophyll spectroscopy: conceptual basis, modern high-resolution approaches, and current challenges.

Reimers, Jeffrey R.; Rätsep, Margus; Linnanto, Juha Matti; Freiberg, Arvi (2022). Proceedings of the Estonian Academy of Sciences, 71 (2), 127−164. DOI: 10.3176/proc.2022.2.04.

2022 | NLP

Machine Translation for Livonian: Catering to 20 Speakers.

Rikters, Matiss; Tomingas, Marili; Tuisk, Tuuli; Ernštreits, Valts; Fishel, Mark (2022). In: Proceedings of the 60th Annual Meeting of the Association for Computational Linguistics, pages 508−514. Association for Computational Linguistics.

2022 | Biology

DNA barcoding of fungal specimens using PacBio long-read high-throughput sequencing.

Runnel, Kadri; Abarenkov, Kessy; Copot, Ovidiu; Mikryukov, Vladimir; Kõljalg, Urmas; Saar, Irja; Tedersoo, Leho (2022). Molecular Ecology Resources, 22 (8), 2871−2879. DOI: 10.1111/1755- 0998.13663.

2022 | NLP

Estonian Text-to-Speech Synthesis with Non-autoregressive Transformers.

Rätsep, Liisa; Lellep, Rasmus; Fishel, Mark (2022). Baltic Journal of Modern Computing, 10 (3), 447−456. DOI: 10.22364/bjmc.2022.10.3.17.

2022 | Chemistry

One Hundred Carboxylate Receptors.

Rüütel, Alo; Tshepelevitsh, Sofja; Leito, Ivo (2022). The Journal of Organic Chemistry, 87 (21), 14186−14193. DOI: 10.1021/acs.joc.2c01725.

2022 | Biology

Additions to Dendrodacrys and outline of taxa with branched hyphidia in Dacrymycetes (Basidiomycota).

Savchenko, Anton; Zamora, Juan C; Alvarenga, Renato; Kõljalg, Urmas; Miettinen, Otto (2022). Fungal Systematics and Evolution, 10, 103−126. DOI: 10.3114/fuse.2022.10.04.

2022 | Medical science

A common founder effect of the splice site variant c.-23+1G > A in GJB2 gene causing autosomal recessive deafness 1A (DFNB1A) in Eurasia.

Solovyev, Aisen, V; Kushniarevich, Alena; Bliznetz, Elena; Bady-Khoo, Marita; Lalayants, Maria R; Markova, Tatiana G; Minarik, Gabriel; Kadasi, L’udevit; Metspalu, Ene; Pshennikova, Vera G; Teryutin, Fedor M; Khusnutdinova, Elza K; Poliakov, Alexander; Metspalu, Mait; Posukh, Olga L; Barashkov, Nikolay A; Fedorova, Sardana A (2022). Human Genetics, 141 (3-4). DOI: 10.1007/s00439-021-02405-w.

2022 | Physics

On‐off‐on Control of Molecular Inversion Symmetry via Multi‐stage Protonation: Elucidating Vibronic Laporte Rule.

Stark, Charles W; Rammo, Matt; Trummal, Aleksander; Uudsemaa, Merle; Pahapill, Juri; Sildoja, Meelis-Mait; Tshepelevitsh, Sofja; Leito, Ivo; Young, David C; Szymański, Bartosz; Vakuliuk, Olena; Gryko, Daniel T; Rebane, Aleksander (2022). Angewandte Chemie International Edition, 61 (51), e202212581. DOI: 10.1002/anie.202212581.

2022 | Earth science

Striped texture of submesoscale fields in the northeastern Baltic Proper: Results of very high-resolution modelling for summer season.

Zhurbas, Victor; Väli, Germo; Kuzmina, Natalia (2022). Oceanologia, 64 (1), 1−21. DOI: 10.1016/j.oceano.2021.08.003.

2022 | Computer science

A Survey of End-to-End Driving: Architectures and Training Methods.

Tampuu, Ardi; Matiisen, Tambet; Semikin, Maksym; Fishman, Dmytro; Muhammad, Naveed (2022). IEEE Transactions on Neural Networks and Learning Systems, 33 (4), 1364−1384. DOI: 10.1109/TNNLS.2020.3043505.

2022 | NLP

Cross-lingual Transfer from Large Multilingual Translation Models to Unseen Under-resourced Languages.

Tars, Maali; Tättar, Andre; Fishel, Mark (2022). Baltic Journal of Modern Computing, 10 (3), 435−446. DOI: 10.22364/bjmc.2022.10.3.16.

2022 | Biology

Global patterns in endemicity and vulnerability of soil fungi.

Tedersoo, Leho; Mikryukov, Vladimir; Zizka, Alexander; Bahram, Mohammad; Hagh‐Doust, Niloufar; Anslan, Sten; Prylutskyi, Oleh; Delgado‐Baquerizo, Manuel; Maestre, Fernando T; Pärn, Jaan; Öpik, Maarja; Moora, Mari; Zobel, Martin; Espenberg, Mikk; Mander, Ülo; Khalid, Abdul Nasir; Corrales, Adriana; Agan, Ahto; Vasco‐Palacios, Aída‐M; Saitta, Alessandro … Abarenkov, Kessy (2022). Global Change Biology, 28 (22). DOI: 10.1111/gcb.16398.

2022 | Medical science

Mapping genomic loci implicates genes and synaptic biology in schizophrenia.

Trubetskoy, Vassily; Pardinas, Antonio F; Qi, Ting; Panagiotaropoulou, Georgia; Awasthi, Swapnil; Bigdeli, Tim B; Bryois, Julien; Chen, Chia-Yen; Dennison, Charlotte A; Hall, Lynsey S; Lam, Max; Watanabe, Kyoko; Frei, Oleksandr; Ge, Tian; Harwood, Janet C; Koopmans, Frank; Magnusson, Sigurdur; Richards, Alexander L; Sidorenko, Julia; Wu, Yang … (2022). Nature, 604 (7906), 502−508. DOI: 10.1038/s41586-022-04434-5.

2022 | NLP

Open and Competitive Multilingual Neural Machine Translation in Production.

Tättar, Andre; Purason, Taido; Kuulmets, Hele-Andra; Luhtaru, Agnes; Rätsep, Liisa; Tars, Maali; Pinnis, Marcis; Bergmanis, Toms; Fishel, Mark (2022). Baltic Journal of Modern Computing, 10, pages 422−434. DOI: 10.22364/bjmc.2022.10.3.15.

2022 | Medical science

The 1^st year of the COVID-19 epidemic in Estonia: a population-based nationwide sequential/consecutive cross-sectional study.

Uusküla, Anneli; Kalda, Ruth; Solvak, Mihkel; Jürisson, Mikk; Käärik, Meelis; Fischer, Krista; Keis, Aime; Raudvere, Uku; Vilo, Jaak; Peterson, Hedi; Käärik, Ene; Metspalu, Mait; Jürgenson, Tuuli; Milani, Lili; Kolberg, Liis; Tiit, Ene M; Vassil, Kristjan (2022). Public Health, 205, 150−156. DOI: 10.1016/j.puhe.2022.02.004.

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