NeuroData's MR Graphs package, m2g, is a turn-key pipeline which uses structural and diffusion MRI data to estimate multi-resolution connectomes reliably and scalably.

• Overview
• Documentation
• System Requirements
• Installation Guide
• Usage
• License
• Issues
• Citing m2g

The m2g pipeline has been developed as a beginner-friendly solution for human connectome estimation by providing robust and reliable estimates of connectivity across a wide range of datasets. The pipelines are explained and derivatives analyzed in our pre-print, available on BiorXiv.

Check out some resources on our website, or our function reference for more information about m2g.

m2g pipelines requires only a standard computer with enough RAM (< 16 GB).

The m2g pipeline:

• was developed and tested primarily on Mac OS (10,11), Ubuntu (16, 18, 20), and CentOS (5, 6);
• made to work on Python 3.7-3.10;
• is wrapped in a Docker container;
• has install instructions via a Dockerfile;
• requires no non-standard hardware to run;
• has key features built upon FSL, AFNI, INDI, Dipy, Nibabel, Nilearn, Networkx, Numpy, Scipy, Scikit-Learn, and others
  • For Python package version numbers, see requirements.txt
  • For binaries required to install AFNI, FSL, INDI, ICA_AROMA, see the Dockerfile
• takes approximately 1-core, < 16-GB of RAM, and 1-2 hours to run for most datasets (varies based on data).

Instructions can be found within our documentation: https://docs.neurodata.io/m2g/install.html

Instructions can be found within our documentation and a demo can be found here.

This project is covered under the Polyform License.

If you're having trouble, notice a bug, or want to contribute (such as a fix to the bug you may have just found) feel free to open a git issue or pull request. Enjoy!

If you find m2g useful in your work, please cite the package via the m2g paper

Chung, J., Lawrence, R., Loftus, A., Kiar, G., Bridgeford, E. W., Roncal, W. G., Chandrashekhar, V., ... & Consortium for Reliability and Reproducibility (CoRR). (2024). A low-resource reliable pipeline to democratize multi-modal connectome estimation and analysis. bioRxiv, 2024-04.