HTTP/2 301
date: Sun, 18 Jan 2026 07:22:26 GMT
content-length: 0
location: https://doi.org/10.1038/483134A
server: cloudflare
vary: Origin
expires: Mon, 19 Jan 2026 07:22:26 GMT
permissions-policy: interest-cohort=(),browsing-topics=()
cf-cache-status: DYNAMIC
nel: {"report_to":"cf-nel","success_fraction":0.0,"max_age":604800}
strict-transport-security: max-age=31536000; includeSubDomains; preload
report-to: {"group":"cf-nel","max_age":604800,"endpoints":[{"url":"https://a.nel.cloudflare.com/report/v4?s=PVBrrQQyFoN5JhFbwqxh%2BZxnkV3Q4xw8ggoqo%2Bn5odH69D8dqUIOp8s%2FaRlIH6XP0XvJgWRLfXZK%2F28IXW96%2BYSt5iWdiQ%3D%3D"}]}
cf-ray: 9bfc5758fefcc17c-BLR
alt-svc: h3=":443"; ma=86400
HTTP/2 302
date: Sun, 18 Jan 2026 07:22:26 GMT
content-type: text/html;charset=utf-8
location: https://www.nature.com/articles/483134a
server: cloudflare
vary: Origin
vary: Accept
expires: Sun, 18 Jan 2026 08:11:00 GMT
permissions-policy: interest-cohort=(),browsing-topics=()
cf-cache-status: DYNAMIC
nel: {"report_to":"cf-nel","success_fraction":0.0,"max_age":604800}
strict-transport-security: max-age=31536000; includeSubDomains; preload
report-to: {"group":"cf-nel","max_age":604800,"endpoints":[{"url":"https://a.nel.cloudflare.com/report/v4?s=fZsGJ1LduoPvcLvNUAoQMe0vbeP%2B%2FhUs4dX1adHhx8V1Y4j47GEhYl%2FZapozw7I9Zo5W6HC1nbqurw2VeDxkGU0u%2Ffku2A%3D%3D"}]}
cf-ray: 9bfc575a9f9cc17c-BLR
alt-svc: h3=":443"; ma=86400
HTTP/2 303
strict-transport-security: max-age=31536000;preload
x-vcap-request-id: 95cbd6f0-4ed7-40e1-7ba3-ae903c4718aa
server: Oscar Platform 0.2039.0
via: 1.1 google, 1.1 varnish
content-type: text/html
location: https://idp.nature.com/authorize?response_type=cookie&client_id=grover&redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2F483134a
accept-ranges: bytes
date: Sun, 18 Jan 2026 07:22:27 GMT
x-served-by: cache-bom-vanm7210076-BOM, cache-bom-vanm7210092-BOM
x-cache: MISS, MISS
x-cache-hits: 0, 0
x-timer: S1768720947.686719,VS0,VE415
vary: x-forwarded-host, upgrade-insecure-requests
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
content-length: 150
HTTP/2 302
cache-control: no-cache, no-store, max-age=0, must-revalidate
content-security-policy: frame-ancestors 'none';
expires: 0
location: https://idp.nature.com/transit?redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2F483134a&code=86e2f69c-4f87-4c84-8c1e-9c58e00145a7
pragma: no-cache
set-cookie: idp_session=sVERSION_13778aed8-5d7a-4b04-b519-e9159a713649; Domain=.nature.com; Path=/; Secure; SameSite=None; HttpOnly
set-cookie: idp_session_http=hVERSION_1e0a0b86d-c67a-4349-af07-7a2b556d1997; Domain=.nature.com; Path=/; HttpOnly
set-cookie: idp_marker=f965906a-8975-4d14-b2fe-551ab703fc3b; Domain=.nature.com; Path=/; Max-Age=34560000; HttpOnly
strict-transport-security: max-age=31536000 ; includeSubDomains
traceparent: 00-d69576be76e441756730d4985213ecd2-134756593fb1b008-01
x-content-type-options: nosniff
x-frame-options: DENY
x-vcap-request-id: d69576be-76e4-4175-6730-d4985213ecd2
x-xss-protection: 1; mode=block
via: 1.1 google, 1.1 varnish
x-cdn-origin: SNPaaS
accept-ranges: bytes
date: Sun, 18 Jan 2026 07:22:27 GMT
x-served-by: cache-bom-vanm7210077-BOM
x-cache: MISS
x-cache-hits: 0
x-timer: S1768720947.175296,VS0,VE394
vary: x-forwarded-proto
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
content-length: 0
HTTP/2 302
cache-control: no-cache, no-store, max-age=0, must-revalidate
content-language: en-US
content-security-policy: frame-ancestors 'none';
expires: 0
location: https://www.nature.com/articles/483134a
pragma: no-cache
strict-transport-security: max-age=31536000 ; includeSubDomains
traceparent: 00-c277f223e5bd49395f5d72cd168419d4-b082b0e73fb990a1-01
x-content-type-options: nosniff
x-frame-options: DENY
x-vcap-request-id: c277f223-e5bd-4939-5f5d-72cd168419d4
x-xss-protection: 1; mode=block
via: 1.1 google, 1.1 varnish
x-cdn-origin: SNPaaS
accept-ranges: bytes
date: Sun, 18 Jan 2026 07:22:27 GMT
x-served-by: cache-bom-vanm7210077-BOM
x-cache: MISS
x-cache-hits: 0
x-timer: S1768720948.582647,VS0,VE382
vary: x-forwarded-proto
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
content-length: 0
HTTP/2 200
content-encoding: gzip
x-b3-sampled: 1
x-content-type-options: nosniff
set-cookie: CONTENT_USAGE_SESSIONID="utterlyidle:v1:ZmIxZjg4MmItOGRiZi00ZWQ4LWExMjYtZGU2ZjA0NTM3NWFl"; Domain=.nature.com; Path=/; Secure=; HttpOnly=
set-cookie: user.uuid.v2="d2046e63-b2d7-467d-a30a-6961753eaf1d"; Expires=Sat, 18 Apr 2026 07:22:28 GMT; Path=/; secure; HttpOnly
content-type: text/html; charset="UTF-8"
x-frame-options: DENY
x-sn-servicetimems: 316
x-b3-traceid: feffb36bbff21a8d
x-forwarded-host: www.nature.com
x-xss-protection: 1; mode=block
server: Oscar Platform 0.2039.0
tracestate: gorouter=9abc0f7782b451ba
tracestate: gorouter=9abc0f7782b451ba
x-b3-spanid: 020814ad0bf43b0b
x-dump-request-bodies: 0
x-vcap-request-id: b7b549c3-93a9-4c46-5dfa-221f755fa8ee
cache-control: private, must-revalidate
via: 1.1 google, 1.1 varnish
accept-ranges: bytes
traceparent: 00-b7b549c393a94c465dfa221f755fa8ee-0e5b0a645e16015d-01
traceparent: 00-b7b549c393a94c465dfa221f755fa8ee-308e063ef4166159-01
strict-transport-security: max-age=31536000;preload
age: 0
date: Sun, 18 Jan 2026 07:22:28 GMT
x-served-by: cache-bom-vanm7210076-BOM, cache-bom-vanm7210092-BOM
x-cache: MISS, MISS, MISS
x-cache-hits: 0, 0
x-timer: S1768720948.978752,VS0,VE823
vary: X-Frame-Options,X-Oscar-Cache-Mode, Accept-Encoding
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
Trouble at the text mine | Nature
Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
A Correction to this article was published on 14 March 2012
Computers can rapidly scan through thousands of research papers to make useful connections, but work is being slowed by publishers' unease.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
Xavier Blanc , Tinh-Hai Collet … Jacques Cornuz
BMC Medical Informatics and Decision Making
Open Access
09 August 2014
Chris J Stubben & Jean F Challacombe
BMC Bioinformatics
Open Access
05 February 2014
Access options
Subscribe to this journal
Receive 51 print issues and online access
185,98 € per year
only 3,65 € per issue
Buy this article
Purchase on SpringerLink Instant access to the full article PDF. Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Change history 08 March 2012 In the original article, the BioNOT project was incorrectly located at the University of Wisconsin-Madison instead of the University of Wisconsin-Milwaukee. This has now been changed.
Authors Richard Van Noorden
This article is cited by
Chris J Stubben Jean F Challacombe
BMC Bioinformatics (2014)
Xavier Blanc Tinh-Hai Collet Jacques Cornuz
BMC Medical Informatics and Decision Making (2014)
Scientometrics (2014)
Nature Biotechnology (2012)