HTTP/2 301
date: Sun, 18 Jan 2026 17:48:29 GMT
content-length: 0
location: https://doi.org/10.1038/NATURE.2017.21765
server: cloudflare
vary: Origin
expires: Mon, 19 Jan 2026 17:48:29 GMT
permissions-policy: interest-cohort=(),browsing-topics=()
cf-cache-status: DYNAMIC
nel: {"report_to":"cf-nel","success_fraction":0.0,"max_age":604800}
strict-transport-security: max-age=31536000; includeSubDomains; preload
report-to: {"group":"cf-nel","max_age":604800,"endpoints":[{"url":"https://a.nel.cloudflare.com/report/v4?s=9kbxnRVSjVfdFnPKW1Jfidv8Eeu0cqkW0ceUQfoS%2BZUqBDMug3y%2B48LCUQuVaEmpqfTiA0Bedc3PoOCjo80V3NHp%2FjHZjQ%3D%3D"}]}
cf-ray: 9bffec690e1b8087-BLR
alt-svc: h3=":443"; ma=86400
HTTP/2 302
date: Sun, 18 Jan 2026 17:48:29 GMT
content-type: text/html;charset=utf-8
location: https://www.nature.com/articles/nature.2017.21765
server: cloudflare
vary: Origin
vary: Accept
expires: Sun, 18 Jan 2026 18:11:00 GMT
permissions-policy: interest-cohort=(),browsing-topics=()
cf-cache-status: DYNAMIC
nel: {"report_to":"cf-nel","success_fraction":0.0,"max_age":604800}
strict-transport-security: max-age=31536000; includeSubDomains; preload
report-to: {"group":"cf-nel","max_age":604800,"endpoints":[{"url":"https://a.nel.cloudflare.com/report/v4?s=Ct5Ec7esHCuMCBV%2FPgnW4zLO4m%2F7n%2ByQ5R9g5JfLRywo%2BNOTQlKWTiQWBJjWgTJSPcxofe4WKbmzb9qaHdA1lJB1QuTCuQ%3D%3D"}]}
cf-ray: 9bffec695e678087-BLR
alt-svc: h3=":443"; ma=86400
HTTP/2 303
strict-transport-security: max-age=31536000;preload
x-vcap-request-id: d3567b24-95e7-42db-7055-5a8a9d1c5e4c
server: Oscar Platform 0.2039.0
via: 1.1 google, 1.1 varnish
content-type: text/html
location: https://idp.nature.com/authorize?response_type=cookie&client_id=grover&redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fnature.2017.21765
accept-ranges: bytes
date: Sun, 18 Jan 2026 17:48:29 GMT
x-served-by: cache-bom-vanm7210074-BOM, cache-bom-vanm7210085-BOM
x-cache: MISS, MISS
x-cache-hits: 0, 0
x-timer: S1768758509.364684,VS0,VE418
vary: x-forwarded-host, upgrade-insecure-requests
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
content-length: 150
HTTP/2 302
cache-control: no-cache, no-store, max-age=0, must-revalidate
content-security-policy: frame-ancestors 'none';
expires: 0
location: https://idp.nature.com/transit?redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fnature.2017.21765&code=365ce86f-d067-4f76-a76a-965b5a293fd5
pragma: no-cache
set-cookie: idp_session=sVERSION_181343621-9ae8-4cce-b62b-6765325ac49c; Domain=.nature.com; Path=/; Secure; SameSite=None; HttpOnly
set-cookie: idp_session_http=hVERSION_1e186ebab-0e72-4b20-a60b-c311ae319747; Domain=.nature.com; Path=/; HttpOnly
set-cookie: idp_marker=a3bb7d9e-e85a-4269-9f71-b79bda39da98; Domain=.nature.com; Path=/; Max-Age=34560000; HttpOnly
strict-transport-security: max-age=31536000 ; includeSubDomains
traceparent: 00-fd8337cbdb3e4acf73282f0aebd31047-ae51bc90f4ac123a-01
x-content-type-options: nosniff
x-frame-options: DENY
x-vcap-request-id: fd8337cb-db3e-4acf-7328-2f0aebd31047
x-xss-protection: 1; mode=block
via: 1.1 google, 1.1 varnish
x-cdn-origin: SNPaaS
accept-ranges: bytes
date: Sun, 18 Jan 2026 17:48:30 GMT
x-served-by: cache-bom-vanm7210027-BOM
x-cache: MISS
x-cache-hits: 0
x-timer: S1768758510.852035,VS0,VE378
vary: x-forwarded-proto
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
content-length: 0
HTTP/2 302
cache-control: no-cache, no-store, max-age=0, must-revalidate
content-language: en-US
content-security-policy: frame-ancestors 'none';
expires: 0
location: https://www.nature.com/articles/nature.2017.21765
pragma: no-cache
strict-transport-security: max-age=31536000 ; includeSubDomains
traceparent: 00-b515df64380d458e43c4de2f65b95b9c-9409d200ba2c2462-01
x-content-type-options: nosniff
x-frame-options: DENY
x-vcap-request-id: b515df64-380d-458e-43c4-de2f65b95b9c
x-xss-protection: 1; mode=block
via: 1.1 google, 1.1 varnish
x-cdn-origin: SNPaaS
accept-ranges: bytes
date: Sun, 18 Jan 2026 17:48:30 GMT
x-served-by: cache-bom-vanm7210027-BOM
x-cache: MISS
x-cache-hits: 0
x-timer: S1768758510.244508,VS0,VE366
vary: x-forwarded-proto
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
content-length: 0
HTTP/2 200
content-encoding: gzip
x-b3-sampled: 1
x-content-type-options: nosniff
set-cookie: CONTENT_USAGE_SESSIONID="utterlyidle:v1:N2Y2NTYxM2YtMDYwMC00OTUyLTljZDItMTY1N2Q2OTVjYTJj"; Domain=.nature.com; Path=/; Secure=; HttpOnly=
set-cookie: user.uuid.v2="b0ded7ae-0ff7-4bc6-b0fd-f549ba0d05b2"; Expires=Sat, 18 Apr 2026 17:48:30 GMT; Path=/; secure; HttpOnly
content-type: text/html; charset="UTF-8"
x-frame-options: DENY
x-sn-servicetimems: 124
x-b3-traceid: 83bb1da5dac47f16
x-forwarded-host: www.nature.com
x-xss-protection: 1; mode=block
server: Oscar Platform 0.2039.0
tracestate: gorouter=5037e1ff9ea0524c
tracestate: gorouter=5037e1ff9ea0524c
x-b3-spanid: fed76f25521a2e72
x-dump-request-bodies: 0
x-vcap-request-id: deb52bfe-eb44-42f6-4cca-b24459c3ef31
cache-control: private, must-revalidate
via: 1.1 google, 1.1 varnish
accept-ranges: bytes
traceparent: 00-deb52bfeeb4442f64ccab24459c3ef31-6b5d130cba85b3c8-01
traceparent: 00-deb52bfeeb4442f64ccab24459c3ef31-0b284fc762792060-01
strict-transport-security: max-age=31536000;preload
age: 0
date: Sun, 18 Jan 2026 17:48:31 GMT
x-served-by: cache-bom-vanm7210074-BOM, cache-bom-vanm7210085-BOM
x-cache: MISS, MISS, MISS
x-cache-hits: 0, 0
x-timer: S1768758511.624931,VS0,VE625
vary: X-Frame-Options,X-Oscar-Cache-Mode, Accept-Encoding
alt-svc: h3=":443";ma=86400,h3-29=":443";ma=86400,h3-27=":443";ma=86400
Unpaywall finds free versions of paywalled papers | Nature
Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
New tool joins a growing collection of software for accessing fee-for-view scientific literature.
Enjoying our latest content?
Access the most recent journalism from Nature's award-winning team
Explore the latest features & opinion covering groundbreaking research
or
Authors Dalmeet Singh Chawla Related links
Related links Related links in Nature Research Related external links
