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Check out our recent publication: The DO-KB knowledgebase 2026 update: expanding programmatic and language access
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The Disease Ontology Knowledgebase (DO-KB)
Explore the DO's semantically defined disease knowledgebase, mine disease-to-disease relatedness through defined features and mechanisms via DO-KB tools.
Disease Ontology
Discover disease knowledge, search the DO's OWL and OBO etiology-based disease classification English and Spanish DAGs.
Join the DO-KB community
Join the DO Community!! Request a new disease term, tell us about your project, and check out our tutorials.
Latest Release Data
Download the DO's monthly data release. DO's end-of-the-month releases include over 130 OBO, OWL and JSON ontology files, DO subsets, DO reports and DO translation source files. Check out the latest release statisitics and release summary of nomenclature updates, re-classifications and new disease terms.
Explore the Disease Ontology
