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epitope - definition and meaning
Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
noun
from Wiktionary , Creative Commons Attribution/Share-Alike License.
noun biochemistry That part of a biomolecule (such as a protein ) that is the target of an immune response
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
noun
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
[epi– + Greek topos , place, spot.]
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Examples
This recombinant protein was used since deletion of the internal epitope between amino acids 433 and 447, called epitope 1443, increases the production of neutralizing antibodies in mouse models of infection
PLoS ONE Alerts: New Articles Laura Ratier et al. 2008
T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease.
The Autoimmune Epidemic Donna Jackson Nakazawa 2008
T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease.
The Autoimmune Epidemic Donna Jackson Nakazawa 2008
Taking into account the circulating B cells and calculating the quantity of antibody per immunologically-distinct epitope , the conclusion was that an infant could mount a response to the antigens present in “10 000 vaccines”.
On Thursday, the Legg report will be published along with... 2008
Although these features are inconsequential for the use of DsRed as a reporter of gene expression, the usefulness of DsRed as an epitope tag is severely limited.
Archive 2005-10-01 2005
Unfortunately, this protein is an obligate tetramer, making it less suitable fur use as an epitope tag than PA-GFP.
Archive 2005-10-01 2005
HVTN said the vaccine candidate was a multi-epitope vaccine developed by Epimmune, a San Diego-based pharmaceutical company.
ANC Daily News Briefing 2003
The library's diversity is expected to result in antibodies against previously inaccessible target molecules and unique epitope coverage.
Reuters: Press Release 2011
All cTnI constructs were derived from the full-length rodent sequence and tagged with C-terminal Flag epitope (DYKDDDDK, Sigma) to distinguish the recombinant from the native cTnI; while, the Tm mutants were engineered into the full-length human Tm
PLoS ONE Alerts: New Articles Jennifer Davis et al. 2010
G159D cTnC was subcloned into the pDC315 AdMax shuttle vector (Microbix Biosystems Inc.) with and without an HA (Hemagglutinin) epitope tag as previously described
PLoS ONE Alerts: New Articles Jennifer Davis et al. 2010
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